l-Stepholidine

Base Information

Chemical Name:l-Stepholidine
CAS No.:16562-13-3
Molecular Formula:C₁₉H₂₁NO₄
Molecular Weight:327.38
Hs Code.:2933990090
UNII:0UPX3E69W8
Nikkaji Number:J28.567F
Wikipedia:Stepholidine
Wikidata:Q27088886
Pharos Ligand ID:1JB6VNR5QHCP
Metabolomics Workbench ID:138600
ChEMBL ID:CHEMBL487387
Mol file:16562-13-3.mol

Synonyms:(-)-stepholidine;L-stepholidine;stepholidine

Suppliers and Price of l-Stepholidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
L-Stepholidine
5mg
$ 2860.00

Medical Isotopes, Inc.
L-Stepholidine
5 mg
$ 290.00

JR MediChem
L-Stepholidine 98%
20mg
$ 1500.00

DC Chemicals
L-Stepholidine >98%,StandardReferencesGrade
20 mg
$ 280.00

Crysdot
L-Stepholidine 98+%
5mg
$ 594.00

Cayman Chemical
(–)-Stepholidine
5mg
$ 1995.00

Cayman Chemical
(–)-Stepholidine
1mg
$ 485.00

Cayman Chemical
(–)-Stepholidine
500μg
$ 285.00

Biosynth Carbosynth
L-Stepholidine
10 mg
$ 200.00

Biosynth Carbosynth
L-Stepholidine
5 mg
$ 140.00

Total 66 raw suppliers

Chemical Property of l-Stepholidine

Chemical Property:

Vapor Pressure:1.34E-11mmHg at 25°C
Melting Point:120-122°C
Refractive Index:1.679
Boiling Point:524 °C at 760 mmHg
PKA:9.97±0.20(Predicted)
Flash Point:270.7 °C
PSA：62.16000
Density:1.37 g/cm³
LogP:2.70840
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:327.14705815
Heavy Atom Count:24
Complexity:447

Purity/Quality:

99%, ^*data from raw suppliers

L-Stepholidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C2C3CC4=C(CN3CCC2=C1)C(=C(C=C4)O)OC)O
Isomeric SMILES:COC1=C(C=C2[C@@H]3CC4=C(CN3CCC2=C1)C(=C(C=C4)O)OC)O
Description A new alkaloid of the protoberberine group, this base occurs in Stephania giabra. The structure has been assigned on the basis of chemical and spectroscopic evidence.
Uses Agonist; antagonist A tetrahydroprotoberberine agonist at dopamine D1 and antagonist at D2 receptors. dyskinesia which is produced by L-DOPA or medicine to treat schizophrenia. Antipsychotics. A tetrahydroprotoberberine agonist at dopamine D1 and antagonist at D2 receptors. It is used for preventing or treating neural diseases. The neural diseases comprise parkinsonism, schizophrenia and dyskinesia which is produced by L-DOPA or medicine to treat schizophrenia. Antipsychotics.

Technology Process of l-Stepholidine

There total 89 articles about l-Stepholidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: (-)-2-benzyloxy-10-hydroxy-3,9-dimethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine

: 16562-14-4,66142-83-4,16562-13-3
(-)-stepholidine

Guidance literature:: With Raney-Ni; In methanol; Reagent/catalyst;

Reference yield: 92.5%

: 2-benzyloxy-10-hydroxy-3,9-dimethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine L-tartaric acid salt

: 16562-14-4,66142-83-4,16562-13-3
(-)-stepholidine

Guidance literature:: With hydrogenchloride; In ethanol; water; Reagent/catalyst; Reflux;

Reference yield: 86.0%

: 1260522-95-9
14-(S)-3,9-dimethoxyl-2,10-diisopropoxy-tetrahydroprotoberberine

: 16562-14-4,66142-83-4,16562-13-3
(-)-stepholidine

Guidance literature:: With boron trichloride; In dichloromethane; at -78 - 20 ℃; optical yield given as %ee; Inert atmosphere;
DOI:10.3987/COM-10-12056