alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-4-morpholinepropanamine

Base Information

Chemical Name:alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-4-morpholinepropanamine
CAS No.:86684-30-2
Molecular Formula:C17H23 N3 O2
Molecular Weight:301.38
Hs Code.:
DSSTox Substance ID:DTXSID501007022
Mol file:86684-30-2.mol

Synonyms:BRN 5756628;86684-30-2;alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-4-morpholinepropanamine;4-Morpholinepropanamine, alpha-methyl-N-(3-phenyl-5-isoxazolyl)-;DTXSID501007022;LS-93328;N-[4-(MORPHOLIN-4-YL)BUTAN-2-YL]-3-PHENYL-1,2-OXAZOL-5-AMINE

Suppliers and Price of alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-4-morpholinepropanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-MORPHOLINEPROPANAMINE, ALPHA-METHYL-N-(3-PHENYL-5-ISOXAZOLYL)- 95.00%
5MG
$ 498.65

Total 3 raw suppliers

Chemical Property of alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-4-morpholinepropanamine

Chemical Property:

Vapor Pressure:1.23E-10mmHg at 25°C
Boiling Point:513°C at 760 mmHg
PKA:7.29±0.10(Predicted)
Flash Point:264.1°C
PSA：50.53000
Density:1.138g/cm³
LogP:2.87520
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:301.17902698
Heavy Atom Count:22
Complexity:317

Purity/Quality:: 4-MORPHOLINEPROPANAMINE, ALPHA-METHYL-N-(3-PHENYL-5-ISOXAZOLYL)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCN1CCOCC1)NC2=CC(=NO2)C3=CC=CC=C3

Technology Process of alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-4-morpholinepropanamine

There total 3 articles about alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-4-morpholinepropanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 86684-00-6
4-<3-(3-phenyl-5-isoxazolyl)aminobutanoyl>morpholine

: 86684-30-2
(1-Methyl-3-morpholin-4-yl-propyl)-(3-phenyl-isoxazol-5-yl)-amine

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In benzene; for 12h; Ambient temperature;
DOI:10.1248/cpb.34.1634

Reference yield:

: 51944-66-2
1-(morpholin-4-yl)but-2-en-1-one

: 86684-30-2
(1-Methyl-3-morpholin-4-yl-propyl)-(3-phenyl-isoxazol-5-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / NaNH₂/benzene / 16 h / Heating

2: 88 percent / 70percent sodium bis-(2-methoxyethoxy)aluminum hydride in toluene / benzene / 12 h / Ambient temperature

With sodium amide; sodium bis(2-methoxyethoxy)aluminium dihydride; benzene; In benzene;
DOI:10.1248/cpb.34.1634

Reference yield:

: 4369-55-5
3-phenyl-isoxazol-5-ylamine

: 86684-30-2
(1-Methyl-3-morpholin-4-yl-propyl)-(3-phenyl-isoxazol-5-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / NaNH₂/benzene / 16 h / Heating

2: 88 percent / 70percent sodium bis-(2-methoxyethoxy)aluminum hydride in toluene / benzene / 12 h / Ambient temperature

With sodium amide; sodium bis(2-methoxyethoxy)aluminium dihydride; benzene; In benzene;
DOI:10.1248/cpb.34.1634