alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-N-(phenylmethyl)-4-morpholinepropanamine

Base Information

Chemical Name:alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-N-(phenylmethyl)-4-morpholinepropanamine
CAS No.:86684-57-3
Molecular Formula:C₂₄H₂₉N₃O₂
Molecular Weight:391.513
Hs Code.:
DSSTox Substance ID:DTXSID901007024
Mol file:86684-57-3.mol

Synonyms:BRN 5646940;alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-N-(phenylmethyl)-4-morpholinepropanamine;4-Morpholinepropanamine, alpha-methyl-N-(3-phenyl-5-isoxazolyl)-N-(phenylmethyl)-;86684-57-3;DTXSID901007024;LS-93331;N-Benzyl-N-[4-(morpholin-4-yl)butan-2-yl]-3-phenyl-1,2-oxazol-5-amine

Suppliers and Price of alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-N-(phenylmethyl)-4-morpholinepropanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-MORPHOLINEPROPANAMINE, ALPHA-METHYL-N-(3-PHENYL-5-ISOXAZOLYL)-N-(PHE NYLMETHYL)- 95.00%
5MG
$ 497.15

Total 0 raw suppliers

Chemical Property of alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-N-(phenylmethyl)-4-morpholinepropanamine

Chemical Property:

Vapor Pressure:1.53E-13mmHg at 25°C
Boiling Point:582.1°C at 760 mmHg
Flash Point:305.9°C
PSA：41.74000
Density:1.138g/cm³
LogP:4.39690
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:391.22597718
Heavy Atom Count:29
Complexity:459

Purity/Quality:: 4-MORPHOLINEPROPANAMINE, ALPHA-METHYL-N-(3-PHENYL-5-ISOXAZOLYL)-N-(PHE NYLMETHYL)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCN1CCOCC1)N(CC2=CC=CC=C2)C3=CC(=NO3)C4=CC=CC=C4

Technology Process of alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-N-(phenylmethyl)-4-morpholinepropanamine

There total 4 articles about alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-N-(phenylmethyl)-4-morpholinepropanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: 100-39-0
benzyl bromide

: 86684-30-2
(1-Methyl-3-morpholin-4-yl-propyl)-(3-phenyl-isoxazol-5-yl)-amine

: 86684-57-3
Benzyl-(1-methyl-3-morpholin-4-yl-propyl)-(3-phenyl-isoxazol-5-yl)-amine

Guidance literature:: With sodium amide; benzene; 1) reflux 1.5 h 2) 50 deg C, 12 h;
DOI:10.1248/cpb.34.1634

Reference yield:

: 51944-66-2
1-(morpholin-4-yl)but-2-en-1-one

: 86684-57-3
Benzyl-(1-methyl-3-morpholin-4-yl-propyl)-(3-phenyl-isoxazol-5-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 63 percent / NaNH₂/benzene / 16 h / Heating

2: 88 percent / 70percent sodium bis-(2-methoxyethoxy)aluminum hydride in toluene / benzene / 12 h / Ambient temperature

3: 27 percent / 1) NaNH₂/benzene / 1) reflux 1.5 h 2) 50 deg C, 12 h

With sodium amide; sodium bis(2-methoxyethoxy)aluminium dihydride; benzene; In benzene;
DOI:10.1248/cpb.34.1634

Reference yield:

: 4369-55-5
3-phenyl-isoxazol-5-ylamine

: 86684-57-3
Benzyl-(1-methyl-3-morpholin-4-yl-propyl)-(3-phenyl-isoxazol-5-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 63 percent / NaNH₂/benzene / 16 h / Heating

2: 88 percent / 70percent sodium bis-(2-methoxyethoxy)aluminum hydride in toluene / benzene / 12 h / Ambient temperature

3: 27 percent / 1) NaNH₂/benzene / 1) reflux 1.5 h 2) 50 deg C, 12 h

With sodium amide; sodium bis(2-methoxyethoxy)aluminium dihydride; benzene; In benzene;
DOI:10.1248/cpb.34.1634