6-(N-Carbobenzoxy-alanyl-alanyl-alanylamido)quinoline

Base Information

Chemical Name:6-(N-Carbobenzoxy-alanyl-alanyl-alanylamido)quinoline
CAS No.:84614-60-8
Molecular Formula:C₂₆H₂₉N₅O₅
Molecular Weight:491.547
Hs Code.:
DSSTox Substance ID:DTXSID50233624
Wikidata:Q83115228
Mol file:84614-60-8.mol

Synonyms:6-(N-carbobenzoxy-alanyl-alanyl-alanylamido)quinoline;6-(N-Cbz-Ala-Ala-Ala-amido)quinoline;CAAAQ

Suppliers and Price of 6-(N-Carbobenzoxy-alanyl-alanyl-alanylamido)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 6-(N-Carbobenzoxy-alanyl-alanyl-alanylamido)quinoline

Chemical Property:

Vapor Pressure:1.26E-22mmHg at 25°C
Boiling Point:754.1°C at 760 mmHg
Flash Point:409.8°C
PSA：147.21000
Density:1.301g/cm³
LogP:3.55680
XLogP3:2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:9
Exact Mass:491.21686904
Heavy Atom Count:36
Complexity:787

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)N(C(C)C(=O)NC1=CC2=C(C=C1)N=CC=C2)C(=O)C(C)NC(=O)OCC3=CC=CC=C3)N
Isomeric SMILES:C[C@@H](C(=O)N([C@@H](C)C(=O)NC1=CC2=C(C=C1)N=CC=C2)C(=O)[C@H](C)NC(=O)OCC3=CC=CC=C3)N

Technology Process of 6-(N-Carbobenzoxy-alanyl-alanyl-alanylamido)quinoline

There total 3 articles about 6-(N-Carbobenzoxy-alanyl-alanyl-alanylamido)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 580-15-4
6-aminoquinoline

: 84614-60-8
6-(N-carbobenzoxy-L-alanyl-L-alanyl-L-alanylamido)quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) 1,1'-carbonyldiimidazole / 1.) THF, RT, 30 min, 2.) THF, 72 h

2: 30percent HBr / acetic acid / 0.5 h / Ambient temperature

3: 1.) 1,1'-carbonyldiimidazole, 2.) Et₃N / 1.) THF, RT, 30 min, 2.) THF, RT, 72 h

With hydrogen bromide; triethylamine; 1,1'-carbonyldiimidazole; In acetic acid;
DOI:10.1021/jm00375a014

Reference yield:

: 84614-59-5
6-(N-carbobenzoxy-L-alanylamido)quinoline

: 84614-60-8
6-(N-carbobenzoxy-L-alanyl-L-alanyl-L-alanylamido)quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 30percent HBr / acetic acid / 0.5 h / Ambient temperature

2: 1.) 1,1'-carbonyldiimidazole, 2.) Et₃N / 1.) THF, RT, 30 min, 2.) THF, RT, 72 h

With hydrogen bromide; triethylamine; 1,1'-carbonyldiimidazole; In acetic acid;
DOI:10.1021/jm00375a014

Reference yield:

: 16012-70-7
benzyloxycarbonyl-L-alanyl-L-alanine

: 90605-99-5
(S)-2-Amino-N-quinolin-6-yl-propionamide; hydrobromide

: 84614-60-8
6-(N-carbobenzoxy-L-alanyl-L-alanyl-L-alanylamido)quinoline

Guidance literature:: With triethylamine; 1,1'-carbonyldiimidazole; Yield given. Multistep reaction; 1.) THF, RT, 30 min, 2.) THF, RT, 72 h;
DOI:10.1021/jm00375a014