N,N-Diethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine

Base Information

Chemical Name:N,N-Diethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine
CAS No.:99008-55-6
Molecular Formula:C₂₀H₂₃N₅O₃
Molecular Weight:381.434
Hs Code.:
DSSTox Substance ID:DTXSID70912904
Nikkaji Number:J527.723J
Wikidata:Q82883357
ChEMBL ID:CHEMBL324351

Synonyms:BRN 5912836;PD 113,377;N,N-Diethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine;Pyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine, N,N-diethyl-9-methoxy-5-nitro-;99008-55-6;CHEMBL324351;SCHEMBL10845895;DTXSID70912904;LS-128926;N,N-Diethyl-2-(9-methoxy-5-nitropyrazolo[3,4,5-kl]acridin-2(1H)-yl)ethan-1-amine;N,N-Diethyl-2-[5-nitro-9-methoxypyrazolo[3,4,5-kl]acridin-2(6H)-yl]ethanamine

Suppliers and Price of N,N-Diethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N,N-Diethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine

Chemical Property:

Vapor Pressure:2.81E-14mmHg at 25°C
Boiling Point:598.3°Cat760mmHg
Flash Point:315.7°C
Density:1.288g/cm³
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:381.18008961
Heavy Atom Count:28
Complexity:554

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCN1C2=C3C(=C(C=C2)[N+](=O)[O-])NC4=C(C3=N1)C=C(C=C4)OC

Technology Process of N,N-Diethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine

There total 5 articles about N,N-Diethyl-9-methoxy-5-nitropyrazolo(3,4,5-kl)acridine-2(6H)-ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 21814-48-2
1-chloro-7-methoxy-4-nitro-10H-acridin-9-one

: 924-29-8
N-[2-(diethylamino)ethyl]hydrazine

: 99008-55-6
N,N-diethyl-9-methoxy-5-nitropyrazolo<3,4,5-kl>acridine-2(6H)-ethanamine

Guidance literature:: In tetrahydrofuran; methanol; at 25 ℃; for 18h;
DOI:10.1021/jm00104a001

Reference yield:

: 55775-97-8
2,6-dichloro-3-nitrobenzoic acid

: 99008-55-6
N,N-diethyl-9-methoxy-5-nitropyrazolo<3,4,5-kl>acridine-2(6H)-ethanamine

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / N,N-dimethylaniline / 18 h / Heating

2: 88 percent / N,N-dimethylaniline, POCl₃ / 1,2-dichloro-ethane / 18 h / Heating

3: 80 percent / tetrahydrofuran; methanol / 18 h / 25 °C

With N,N-dimethyl-aniline; trichlorophosphate; In tetrahydrofuran; methanol; 1,2-dichloro-ethane;
DOI:10.1021/jm00104a001

Reference yield:

: 55776-09-5
6-chloro-2-<(4-methoxyphenyl)amino>-3-nitrobenzoic acid

: 99008-55-6
N,N-diethyl-9-methoxy-5-nitropyrazolo<3,4,5-kl>acridine-2(6H)-ethanamine

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / N,N-dimethylaniline, POCl₃ / 1,2-dichloro-ethane / 18 h / Heating

2: 80 percent / tetrahydrofuran; methanol / 18 h / 25 °C

With N,N-dimethyl-aniline; trichlorophosphate; In tetrahydrofuran; methanol; 1,2-dichloro-ethane;
DOI:10.1021/jm00104a001