Cryptophycin 51

Base Information

Chemical Name:Cryptophycin 51
CAS No.:186256-66-6
Molecular Formula:C₃₆H₄₅ClN₂O₇
Molecular Weight:653.216
Hs Code.:

Synonyms:

Suppliers and Price of Cryptophycin 51

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of Cryptophycin 51

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of Cryptophycin 51

There total 20 articles about Cryptophycin 51 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.4%

: (S)-2-(3-Amino-2,2-dimethyl-propionyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-{(E)-3-[(R)-2-(3-chloro-4-methoxy-phenyl)-1-(2,2,2-trichloro-ethoxycarbonyl)-ethylcarbamoyl]-allyl}-2-methyl-4-phenyl-but-3-enyl ester

: 186256-66-6
cryptophycin-51

: (13E,29E)-(3S,10R,16S,19S,26R,32S)-10,26-Bis-(3-chloro-4-methoxy-benzyl)-3,19-diisobutyl-6,6,22,22-tetramethyl-16,32-bis-((E)-(R)-1-methyl-3-phenyl-allyl)-1,4,17,20-tetraoxa-8,11,24,27-tetraaza-cyclodotriaconta-13,29-dien-2,5,9,12,18,21,25,28-octaone

Guidance literature:: With 2-hydroxypyridin; In toluene; at 20 ℃; for 16h;
DOI:10.1016/S0957-4166(98)00287-0

Reference yield: 80.0%

: (S)-2-(3-tert-Butoxycarbonylamino-2,2-dimethyl-propionyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-{(E)-3-[(R)-2-(3-chloro-4-methoxy-phenyl)-1-(2,2,2-trichloro-ethoxycarbonyl)-ethylcarbamoyl]-allyl}-2-methyl-4-phenyl-but-3-enyl ester

: 186256-66-6
cryptophycin-51

Guidance literature:: (S)-2-(3-tert-Butoxycarbonylamino-2,2-dimethyl-propionyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-{(E)-3-[(R)-2-(3-chloro-4-methoxy-phenyl)-1-(2,2,2-trichloro-ethoxycarbonyl)-ethylcarbamoyl]-allyl}-2-methyl-4-phenyl-but-3-enyl ester; With trifluoroacetic acid;

With 2-hydroxypyridin; Further stages.;
DOI:10.1021/jo9919862