6-Methylene-4-pregnene-3,20-dione

Base Information

Chemical Name:6-Methylene-4-pregnene-3,20-dione
CAS No.:19457-57-9
Molecular Formula:C₂₂H₃₀O₂
Molecular Weight:326.479
Hs Code.:
DSSTox Substance ID:DTXSID00941207
Nikkaji Number:J598.594C
Wikidata:Q82917995
Mol file:19457-57-9.mol

Synonyms:6-methylene-4-pregnene-3,20-dione;6-methylenepregn-4-ene-3,20-dione;6-methyleneprogesterone;LY 207320;LY-207320;LY207320

Suppliers and Price of 6-Methylene-4-pregnene-3,20-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-METHYLENE-4-PREGNENE-3,20-DIONE 95.00%
5MG
$ 500.71

Total 3 raw suppliers

Chemical Property of 6-Methylene-4-pregnene-3,20-dione

Chemical Property:

Vapor Pressure:7.53E-09mmHg at 25°C
Boiling Point:465.7°Cat760mmHg
Flash Point:173.2°C
PSA：34.14000
Density:1.08g/cm³
LogP:4.88960
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:326.224580195
Heavy Atom Count:24
Complexity:657

Purity/Quality:

99% ^*data from raw suppliers

6-METHYLENE-4-PREGNENE-3,20-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1CCC2C1(CCC3C2CC(=C)C4=CC(=O)CCC34C)C
Isomeric SMILES:CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=C)C4=CC(=O)CC[C@]34C)C

Technology Process of 6-Methylene-4-pregnene-3,20-dione

There total 12 articles about 6-Methylene-4-pregnene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57-83-0
Progesterone

: 19457-57-9
6-Methylene Progesterone

Guidance literature:: Multi-step reaction with 3 steps

2: CHCl₃ / 30 h / Heating

3: 1) MeI; 2) DBU

With 1,8-diazabicyclo[5.4.0]undec-7-ene; methyl iodide; In chloroform;
DOI:10.1016/S0040-4039(00)71510-3

Reference yield:

: 79694-58-9
20β-Hydroxy-6-methylene-4-pregnen-3-one

: 19457-57-9
6-Methylene Progesterone

Guidance literature:: With chromium(VI) oxide; sulfuric acid; In acetone; for 0.166667h;
DOI:10.1016/0039-128X(81)90027-1

Reference yield:

: 79694-57-8
20β-Acetoxy-6-methylene-4-pregnen-3-one

: 19457-57-9
6-Methylene Progesterone

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / methanol; tetrahydrofuran; H₂O / 24 h / Ambient temperature

2: CrO₃, conc. H₂SO₄ / acetone / 0.17 h

With chromium(VI) oxide; potassium hydroxide; sulfuric acid; In tetrahydrofuran; methanol; water; acetone;
DOI:10.1016/0039-128X(81)90027-1