Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(pentafluoroethyl)-

Base Information

• Chemical Name: Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(pentafluoroethyl)-
• CAS No.: 55716-11-5
• Molecular Formula: C6F13NO
• Molecular Weight: 349.051
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID0069042
• Nikkaji Number: J792.012A
• Wikidata: Q81995834
• Mol file: 55716-11-5.mol

Synonyms:Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(pentafluoroethyl)-;55716-11-5;Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(1,1,2,2,2-pentafluoroethyl)-;Perfluoro-4-ethylmorpholine;perfluoro(4-ethylmorpholine);C6F13NO;SCHEMBL4911427;DTXSID0069042;BMPMIPFMFUBMNZ-UHFFFAOYSA-N;C6-F13-N-O;4-(Pentafluoroethyl)-2,2,3,3,5,5,6,6-octafluoromorpholine

Chemical Property of Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(pentafluoroethyl)-

Chemical Property:

• Vapor Pressure: 412mmHg at 25°C
• Boiling Point: 41.1°C at 760 mmHg
• PSA: 12.47000
• Density: 1.82g/cm³
• LogP: 3.78280
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 15
• Rotatable Bond Count: 1
• Exact Mass: 348.9772297
• Heavy Atom Count: 21
• Complexity: 399

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(C(OC(C(N1C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F

Technology Process of Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(pentafluoroethyl)-

There total 14 articles about Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(pentafluoroethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.7%

(2-methyl-3-morpholin-4-yl)propionic acid methyl ester (20120-26-7) → perfluoro(N-ethylmorpholine) (55716-11-5) + perfluorodiethyl ether (358-21-4) + 2,2,3,3,5,5,6,6-Octafluoro-4-trifluoromethyl-morpholine (382-28-5) + 2-[difluoro-(2,2,3,3, 5,5,6,6-octafluoromorpholin-4-yl)methyl]-2,3,3,3-tetrafluoro-propanoyl fluoride (122531-27-5)

Guidance literature:

With hydrogen fluoride; at 7 - 8 ℃; for 7.53333h; Further byproducts given; electrochemical reaction; anodic current density of 3.5 A dm^-2, a cell voltage of 7.1 V - 7.6 V;

DOI:10.1016/0022-1139(93)03019-I

Reference yield: 43.2%

methyl 3-methyl-3-morpholinylpropionate (33611-45-9) → perfluoro(N-ethylmorpholine) (55716-11-5) + perfluorodiethyl ether (358-21-4) + perfluoro(3-morpholinooxalane) + perfluoro(3-morpholino-n-butyryl fluoride) (123337-59-7)

Guidance literature:

With hydrogen fluoride; at 7 - 8 ℃; for 8.83333h; Further byproducts given; electrochemical reaction; anodic current density of 3.5 A dm^-2, a cell voltage of 7.2 V - 7.6 V;

DOI:10.1016/0022-1139(93)03019-I

Reference yield: 17.6%

N-ethyl-N,N-bis(ethyltrimethylsilylether) → perfluoro(N-ethylmorpholine) (55716-11-5) + perfluorodiethyl ether (358-21-4) + 2,2,3,3,5,5,6,6-Octafluoro-4-trifluoromethyl-morpholine (382-28-5) + 2,2-difluoro-2-(2,2,3,3,5,5,6,6-octafluoromorpholin-4-yl)acetyl fluoride (130279-34-4)

Guidance literature:

With hydrogen fluoride; at 7 - 8 ℃; for 10.8333h; Electrochemical reaction;

DOI:10.1016/S0022-1139(99)00106-2

upstream raw materials:

methyl 3-morpholinopropionate

N,N-diethylglycine methyl ester

2-morpholinopropionic acid methyl ester

(2-methyl-3-morpholin-4-yl)propionic acid methyl ester