(1R,4S,5R,12S,13R)-1,5-Dimethyl-9-methylidene-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one

Base Information

Chemical Name:(1R,4S,5R,12S,13R)-1,5-Dimethyl-9-methylidene-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one
CAS No.:101020-89-7
Molecular Formula:C15H20 O5
Molecular Weight:280.321
Hs Code.:
DSSTox Substance ID:DTXSID20905902
Mol file:101020-89-7.mol

Synonyms:artemisitene

Suppliers and Price of (1R,4S,5R,12S,13R)-1,5-Dimethyl-9-methylidene-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Artemisitene
250mg
$ 1940.00

Biosynth Carbosynth
Artemisitene
25 mg
$ 500.00

Biosynth Carbosynth
Artemisitene
10 mg
$ 280.00

Biosynth Carbosynth
Artemisitene
5 mg
$ 190.00

Biosynth Carbosynth
Artemisitene
2 mg
$ 96.00

Biosynth Carbosynth
Artemisitene
1 mg
$ 60.00

Total 22 raw suppliers

Chemical Property of (1R,4S,5R,12S,13R)-1,5-Dimethyl-9-methylidene-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one

Chemical Property:

Vapor Pressure:3.52E-07mmHg at 25°C
Boiling Point:417.5°Cat760mmHg
Flash Point:185.9°C
PSA：53.99000
Density:1.26g/cm³
LogP:2.31500
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:280.13107373
Heavy Atom Count:20
Complexity:489

Purity/Quality:

99%, ^*data from raw suppliers

Artemisitene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC2C(=C)C(=O)OC3C24C1CCC(O3)(OO4)C
Isomeric SMILES:C[C@@H]1CCC2C(=C)C(=O)O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C
Uses Artemisitene, the oxidized form of Artemisinin (A777500), exists as a minor constituent in an American variant of Artemisia annua. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinic acid, Artemisinin B, Artemisitene, etc. An antimalarial agent.

Technology Process of (1R,4S,5R,12S,13R)-1,5-Dimethyl-9-methylidene-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one

There total 10 articles about (1R,4S,5R,12S,13R)-1,5-Dimethyl-9-methylidene-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%