(S)-3-Azido-2-benzylpropanol

Base Information

• Chemical Name: (S)-3-Azido-2-benzylpropanol
• CAS No.: 173216-46-1
• Molecular Formula: C10H13N3O
• Molecular Weight: 191.2297
• DSSTox Substance ID: DTXSID10169556
• Wikidata: Q83039274
• Mol file: 173216-46-1.mol

Synonyms:(S)-3-Azido-2-benzylpropanol;173216-46-1;CCRIS 8040;DTXSID10169556

Chemical Property of (S)-3-Azido-2-benzylpropanol

Chemical Property:

• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 191.105862047
• Heavy Atom Count: 14
• Complexity: 196

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(CN=[N+]=[N-])CO
• Isomeric SMILES: C1=CC=C(C=C1)C[C@@H](CN=[N+]=[N-])CO

Technology Process of (S)-3-Azido-2-benzylpropanol

There total 12 articles about (S)-3-Azido-2-benzylpropanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(R)-1-acetoxy-3-azido-2-benzylpropane (254990-76-6) → (R)-3-azido-2-benzylpropanol (173216-45-0,173216-46-1)

Guidance literature:

With lipase Amano P; pH 7 buffer; at 20 ℃; for 22h; pH=7;

DOI:10.1016/S0957-4166(99)00371-7

Reference yield: 98.0%

3-azido-2-benzylpropyl acetate (289902-92-7) → 3-azido-2-benzyl-1-propanol (289902-96-1,173216-46-1)

Guidance literature:

With potassium carbonate; In methanol; water; at 20 ℃; for 2h;

DOI:10.1016/S0968-0896(00)00216-9

Reference yield: 98.0%

→ 3-azido-2-benzyl-1-propanol (289902-96-1,173216-46-1)

Guidance literature:

upstream raw materials:

(2S)-3-azido-2-benzyl-propanal

(R)-1-acetoxy-3-azido-2-benzylpropane

(R)-3-acetoxy-2-benzyl-1-propanol

(S)-1-acetoxy-2-benzyl-3-(methanesulfonyloxy)propane