Desoxymethyltestosterone

Base Information

Chemical Name:Desoxymethyltestosterone
CAS No.:3275-64-7
Molecular Formula:C20H32O
Molecular Weight:288.473
Hs Code.:
NSC Number:63329
UNII:B9E9G5A169
DSSTox Substance ID:DTXSID50872931
Nikkaji Number:J58.249B
Wikipedia:Desoxymethyltestosterone
Wikidata:Q904694
Mol file:3275-64-7.mol

Synonyms:17-alpha-5-alpha-androst-2-en-17beta-ol;17-methylandrost-2-en-17-ol;desoxymethyltestosterone;madol

Suppliers and Price of Desoxymethyltestosterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
17-ALPHA-METHYL-ETIOALLOCHOLAN-2-ENE-17-BETA-OL 95.00%
5MG
$ 496.55

Total 39 raw suppliers

Chemical Property of Desoxymethyltestosterone

Chemical Property:

Vapor Pressure:2.72E-07mmHg at 25°C
Melting Point:144-146 °C
Refractive Index:1.531
Boiling Point:378.783 °C at 760 mmHg
PKA:15.16±0.60(Predicted)
Flash Point:160.866 °C
PSA：20.23000
Density:1.02 g/cm³
LogP:4.94620
Storage Temp.:Refrigerator
XLogP3:5.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:288.245315640
Heavy Atom Count:21
Complexity:469

Purity/Quality:

99%, ^*data from raw suppliers

17-ALPHA-METHYL-ETIOALLOCHOLAN-2-ENE-17-BETA-OL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2(C)O)CCC4C3(CC=CC4)C
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(CC=CC4)C
Uses It is an anabolic er as compared to dihydrotestosterone (DHT).

Technology Process of Desoxymethyltestosterone

There total 11 articles about Desoxymethyltestosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 1,8a,10a-trimethylhexadecahydro-1H-cyclopenta[7,8]phenanthro[2,3-b]thiiren-1-ol

: 3275-64-7,6699-63-4
10,13,17-trimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol

Guidance literature:: With water; potassium ethyl xanthogenate; In N,N-dimethyl-formamide; at 130 ℃; for 24h;
DOI:10.1021/acs.orglett.1c02600

Reference yield: 39.0%

: 14639-79-3,24174-20-7,82467-84-3,963-75-7
5α-androst-2-en-17-one

: 75-16-1
methylmagnesium bromide

: 3275-64-7
17β-hydroxy-17α-methyl-5α-androst-2-ene

Guidance literature:: In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

Reference yield:

: 29041-91-6
2α-bromo-17β-hydroxy-5α-androstan-3-one

: 3275-64-7
17β-hydroxy-17α-methyl-5α-androst-2-ene

Guidance literature:: Multi-step reaction with 3 steps

1: (i) NaBH₄, EtOH, (ii) Zn, AcOH, (iii) NaOH, MeOH

2: CrO₃, H₂SO₄ / acetone

3: diethyl ether; benzene

With chromium(VI) oxide; sulfuric acid; In diethyl ether; acetone; benzene;
DOI:10.1021/jm00338a016