Pregnenediol

Base Information

Chemical Name:Pregnenediol
CAS No.:901-56-4
Molecular Formula:C₂₁H₃₄O₂
Molecular Weight:318.5
Hs Code.:
UNII:3Z565YJO1O
DSSTox Substance ID:DTXSID801009158
Nikkaji Number:J121.010F
Wikidata:Q27258244
Metabolomics Workbench ID:35482
ChEMBL ID:CHEMBL4174453
Mol file:901-56-4.mol

Synonyms:20 alpha-dihydropregnenolone;20 beta-dihydropregnenolone;5-pregnene-3,20-diol;5-pregnene-3,20-diol, (3alpha,20alpha)-isomer;5-pregnene-3,20-diol, (3beta)-isomer;5-pregnene-3,20-diol, (3beta,20beta)-isomer;5-pregnene-3beta,20alpha-diol

Suppliers and Price of Pregnenediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
20a-Dihydro pregnenolone
5 mg
$ 495.50

Biosynth Carbosynth
20a-Dihydro pregnenolone
2 mg
$ 272.60

Biosynth Carbosynth
20a-Dihydro pregnenolone
1 mg
$ 149.90

Biosynth Carbosynth
20a-Dihydro pregnenolone
25 mg
$ 1638.00

Biosynth Carbosynth
20a-Dihydro pregnenolone
10 mg
$ 900.90

AHH
5-Pregnen-3-beta,20-alpha-diol 98%
5g
$ 558.00

Total 9 raw suppliers

Chemical Property of Pregnenediol

Chemical Property:

Vapor Pressure:6.63E-10mmHg at 25°C
Boiling Point:447.9°Cat760mmHg
Flash Point:198.6°C
PSA：40.46000
Density:1.09g/cm³
LogP:4.30710
XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:318.255880323
Heavy Atom Count:23
Complexity:512

Purity/Quality:

99% ^*data from raw suppliers

20a-Dihydro pregnenolone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)O
Isomeric SMILES:C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)O
Uses 20α-Dihydro Pregnenolone is a metabolite of Pregnenolone (P712200).

Technology Process of Pregnenediol

There total 25 articles about Pregnenediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 145-13-1
Pregnenolone

: 53-43-0
dehydroepiandrosterone

: 521-17-5,1963-03-7,4593-57-1,4593-58-2,14504-94-0,16895-59-3,47122-33-8,64162-67-0,75767-22-5,139973-51-6,151284-19-4
5-androstenediol

: 387-79-1
17-Hydroxypregnenolone

: 1224-94-8
HAD

: 901-57-5,10148-89-7,50897-02-4,59042-34-1,901-56-4
pregn-5-ene-3β,20α-diol

: 520-88-7
(3β,16α)-3,16-dihydroxypregn-5-en-20-one

Guidance literature:: With glucose-6-phosphate dehydrogenase; phosphate buffer; α-D-glucose 6-phosphate; human testicular microsomes (prostatic carcinoma); NADP; Sucrose; at 37 ℃; for 1.33333h; Product distribution; Kinetics; <4-14C>labeled, var. time;
DOI:10.1016/0039-128X(88)90010-4

Reference yield:

: pregnenolone tosylhydrazone

: 901-57-5,10148-89-7,50897-02-4,59042-34-1,901-56-4
pregn-5-ene-3β,20α-diol

: 901-57-5
(20R)-pregn-5-ene-3β,20-diol

Guidance literature:: With sodium tetrahydroborate; In water; isopropyl alcohol; for 16h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;
DOI:10.1246/bcsj.66.3532

Reference yield:

: 145-13-1
Pregnenolone

: 901-57-5,10148-89-7,50897-02-4,59042-34-1,901-56-4
pregn-5-ene-3β,20α-diol

: 901-57-5
(20R)-pregn-5-ene-3β,20-diol

Guidance literature:: With potassium borohydride; tetrabutylammomium bromide; In water; at 60 ℃; for 2h; Product distribution; other reagents, polimeric supports, solvents;
DOI:10.1016/S0040-4020(97)00011-2