2,2,2',4'-Tetrachloroacetophenone

Base Information

Chemical Name:2,2,2',4'-Tetrachloroacetophenone
CAS No.:2274-66-0
Molecular Formula:C8H4Cl4O
Molecular Weight:257.931
Hs Code.:2914700090
European Community (EC) Number:218-890-6
NSC Number:81222
UNII:O43MMI49GE
DSSTox Substance ID:DTXSID9062300
Nikkaji Number:J31.099I
Wikidata:Q27285304
ChEMBL ID:CHEMBL4283949
Mol file:2274-66-0.mol

Synonyms:2,2,2',4'-tetrachloroacetophenone;TCAP

Suppliers and Price of 2,2,2',4'-Tetrachloroacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone
1g
$ 110.00

Rieke Metals
2,2-dichloro-1-(2,4-dichlorophenyl)ethanone
1g
$ 661.00

Medical Isotopes, Inc.
2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone
1 g
$ 610.00

American Custom Chemicals Corporation
2,2,2',4'-TETRACHLOROACETOPHENONE 95.00%
5MG
$ 505.36

AK Scientific
2,2,2',4'-Tetrachloroacetophenone
5g
$ 531.00

Total 32 raw suppliers

Chemical Property of 2,2,2',4'-Tetrachloroacetophenone

Chemical Property:

Boiling Point:310 °C at 760 mmHg
Flash Point:130.2 °C
PSA：17.07000
Density:1.535 g/cm³
LogP:3.97980
Storage Temp.:Refrigerator, Under Inert Atmosphere
Solubility.:Chloroform (Soluble), Methanol (Soluble)
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:257.898675
Heavy Atom Count:13
Complexity:195

Purity/Quality:

98% ^*data from raw suppliers

2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)Cl)C(=O)C(Cl)Cl
Uses 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone is used in the synthesis of acid chloride phenylhydrazones in a broad-spectrum anthelmintic series.

Technology Process of 2,2,2',4'-Tetrachloroacetophenone

There total 5 articles about 2,2,2',4'-Tetrachloroacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 2234-16-4
1-(2,4-dichlorophenyl)ethan-1-one

: 2274-66-0
2,2-dichloro-1-(2,4-dichlorophenyl)ethan-1-one

Guidance literature:: With benzyltrimethylazanium tetrachloro-λ³-iodanuide; acetic acid; at 70 ℃; for 6h;
DOI:10.1246/bcsj.65.2549

Reference yield: 73.0%

: 2234-16-4
1-(2,4-dichlorophenyl)ethan-1-one

: 2274-66-0
2,2-dichloro-1-(2,4-dichlorophenyl)ethan-1-one

: 4252-78-2
2,2',4'-trichloroacetophenone

Guidance literature:: With chloro-trimethyl-silane; potassium nitrate; In dichloromethane; at 60 ℃; for 16h;
DOI:10.1016/j.tetlet.2011.01.039

Reference yield: 39.5%

: 79-36-7
dichloroacethyl chloride

: 541-73-1
1,3-Dichlorobenzene

: 2274-66-0
2,2-dichloro-1-(2,4-dichlorophenyl)ethan-1-one

Guidance literature:: aluminium trichloride; 1.) 60-65 deg C, 4 h; 2.) reflux, 110-115 deg C, 8 h; 3.) 25 deg C, 24 h;
DOI:10.1016/S0040-4020(01)90320-5