2,5-Dimethyl-terephthalic acid dimethyl ester

Base Information

• Chemical Name: 2,5-Dimethyl-terephthalic acid dimethyl ester
• CAS No.: 54100-53-7
• Molecular Formula: C12H14O4
• Molecular Weight: 222.241
• Mol file: 54100-53-7.mol

Synonyms:

Chemical Property of 2,5-Dimethyl-terephthalic acid dimethyl ester

Chemical Property:

• Vapor Pressure: 0.000623mmHg at 25°C
• Melting Point: 114-116 °C
• Boiling Point: 309.9°C at 760 mmHg
• Flash Point: 150°C
• Density: 1.123g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

2,5-DIMETHYL-TEREPHTHALIC ACID DIMETHYL ESTER Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-Dimethyl-terephthalic acid dimethyl ester

There total 5 articles about 2,5-Dimethyl-terephthalic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2,5-dimethylterephthalic acid (6051-66-7) + diazomethyl-trimethyl-silane (18107-18-1) → 2,5-dimethylterephthalic acid, dimethyl ester (54100-53-7)

Guidance literature:

2,5-dimethylterephthalic acid; diazomethyl-trimethyl-silane; In methanol; hexanes; diethyl ether; at 0 - 20 ℃; for 0.5h;

With acetic acid; In methanol; hexanes; diethyl ether;

Reference yield:

2,5-dibromo-p-xylene (1074-24-4) → 2,5-dimethylterephthalic acid, dimethyl ester (54100-53-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 81 percent / dimethylformamide / 48 h / Heating

2: KOH / bis-(2-hydroxy-ethyl) ether / Heating

3: MeSO₃H / 10 h / Heating

With potassium hydroxide; methanesulfonic acid; In N,N-dimethyl-formamide; diethylene glycol;

DOI:10.1021/ja982499r

Reference yield:

2,5-dimethylbenzene-1,4-dicarbonitrile (39095-25-5) → 2,5-dimethylterephthalic acid, dimethyl ester (54100-53-7)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / bis-(2-hydroxy-ethyl) ether / Heating

2: MeSO₃H / 10 h / Heating

With potassium hydroxide; methanesulfonic acid; In diethylene glycol;

DOI:10.1021/ja982499r

upstream raw materials:

methanol

Pyromellitic dianhydride

2,5-dimethylbenzene-1,4-dicarbonitrile

2,5-dibromo-p-xylene

Downstream raw materials:

2,5-dimethylbenzene-1,4-dicarbohydroxamic acid

4-(methoxycarbonyl)-2,5-dimethylbenzoic acid

dimethyl 2,5-dimethyl-3-nitroterephthalate

dimethyl 2,5-bis(bromomethyl)benzene-1,4-dicarboxylate

Refernces

• 1、 Ngola, Sarah M.,Kearney, Patrick C.,Mecozzi, Sandro,Russell, Keith,Dougherty, Dennis A.. "A Selective Receptor for Arginine Derivatives in Aqueous Media. Energetic Consequences of Salt Bridges That Are Highly Exposed to Water". . p. 1192 - 1201. Retrieved 2007/10/03.