2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine oxime

Base Information

• Chemical Name: 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine oxime
• CAS No.: 708-08-7
• Molecular Formula: C₈H₁₀N₂O₃
• Molecular Weight: 182.179
• DSSTox Substance ID: DTXSID801161247
• Mol file: 708-08-7.mol

Synonyms:Maybridge4_003411;Oprea1_185916;SCHEMBL11467416;DTXSID801161247;AKOS024323637;2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine oxime;3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde oxime

Chemical Property of 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine oxime

Chemical Property:

• Vapor Pressure: 1.05E-06mmHg at 25°C
• Boiling Point: 362.1°C at 760 mmHg
• Flash Point: 172.8°C
• PSA: 81.92000
• Density: 1.36g/cm³
• LogP: -0.40460
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 182.06914219
• Heavy Atom Count: 13
• Complexity: 186

Purity/Quality:

99% ^*data from raw suppliers

3-HYDROXY-5-HYDROXYMETHYL-2-METHYL-PYRIDINE-4-CARBALDEHYDE OXIME 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=NC=C(C(=C1O)C=NO)CO

Technology Process of 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine oxime

There total 4 articles about 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

pyridoxal hydrochloride (65-22-5) → Pyridoxaloxime (708-08-7)

Guidance literature:

With hydroxylamine hydrochloride; In ethanol; at 20 ℃; for 0.5h;

DOI:10.1016/j.tetlet.2009.08.086

Reference yield:

pyridoxal (66-72-8) → 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine oxime (20905-66-2,708-08-7)

Guidance literature:

With hydroxylamine hydrochloride; water; sodium acetate;

DOI:10.1021/ja01240a025

Reference yield:

pyridoxal hydrochloride (58-56-0) → 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine oxime (20905-66-2,708-08-7)

Guidance literature:

With manganese(IV) oxide; sulfuric acid; hydroxylamine hydrochloride; Yield given. Multistep reaction; 1.) 5 h, 2.) 70 deg C, 10 min;

DOI:10.1007/BF00780188

upstream raw materials:

pyridoxal

pyridoxal hydrochloride

pyridoxal hydrochloride