Welcome to LookChem.com Sign In|Join Free
  • or

58-56-0

Post Buying Request

58-56-0 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
PyridoxineHCL(VitaminB6)
Cas No: 58-56-0
No Data 1 Kilogram 1-5 Metric Ton/Month EnBridge PharmTech Co., Ltd. Contact Supplier
High quality Vb6 Bp2008 Usp31 Ep6 supplier in China
Cas No: 58-56-0
No Data 1 Kilogram 30 Metric Ton/Month Simagchem Corporation Contact Supplier
Pyridoxine hydrochloride
Cas No: 58-56-0
USD $ 25.0-28.0 / Kilogram 100 Kilogram 500 Metric Ton/Month Arshine Pharmaceutical Co., Limited Contact Supplier
Pyridoxine HCL/Cas:58-56-0/99.9% Vitamin B6 HCL/Pyridoxine hydrochloride
Cas No: 58-56-0
USD $ 2.0-3.0 / Metric Ton 25 Metric Ton 1000 Metric Ton/Day Hubei DiBo chemical co., LTD Contact Supplier
nutritional supplements vitamin b6 pyridoxine/pyridoxine price 58-56-0
Cas No: 58-56-0
No Data 1 Kilogram 500 Metric Ton/Month Shanghai PengMo Biotechnology Co.,Ltd Contact Supplier
Pyridoxine hydrochloride
Cas No: 58-56-0
No Data No Data No Data Cartoon Ingredients Co., Ltd Contact Supplier
Pyridoxine hydrochloride Manufacturer/High quality/Best price/In stock
Cas No: 58-56-0
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High purity Pyridoxine hydrochloride with high quality and best price cas:58-56-0
Cas No: 58-56-0
USD $ 87.0-105.0 / Kilogram 1 Kilogram 99999 Kilogram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
Pyridoxine hydrochloride
Cas No: 58-56-0
USD $ 100.0-100.0 / Kilogram 1 Kilogram 4000 Kilogram/Month Kono Chem Co.,Ltd Contact Supplier
Pyridoxine hydrochloride, Vitamin B6, food additive and USP grade
Cas No: 58-56-0
USD $ 1.0-1.0 / Kilogram 1 Kilogram 10 Metric Ton/Month Hebei yanxi chemical co.,LTD. Contact Supplier

58-56-0 Usage

Uses

One of the vitamins of the B6 complex; present in many foodstuffs (yeast, liver and cereals). It has a role in transporting protein Bsu1, contributes to thiamine uptake; characterization of thiamine (vitamin B1) transporter Thi9 from Schizosaccharomyces p

Uses

Pyridoxine is one of the vitamins of the B6 complex; present in many foodstuffs (yeast, liver and cereals). Pyridoxine has a role in transporting protein Bsu1, Pyridoxine contributes to thiamine uptak e; characterization of thiamine (vitamin B1) transporter Thi9 from Schizosaccharomyces pombe.

Chemical Properties

Crystalline

Purification Methods

Purify the vitamin by recrystallisation from EtOH/Me2CO, n-BuOH or MeOH/Et2O. Its solubility in H2O is 22%, and in EtOH it is 1.1%. It is insoluble in Et2O and CHCl3. Acidic aqueous solutions are stable at 120o/30minute. The free base has m 159-160o after recrystallisation from Me2CO and sublimation at 140-145o/0.0001mm. It has UV max at 290nm ( 84,000), 253 and 325nm ( 3,700 and 7,100) in 0.1N aqueous HCl. [Khua & Wendt Chem Ber 71 780 1938, 72 311 1939, Harris & Folkers J Am Chem Soc 61 1242 1939, Harris et al. J Am Chem Soc 62 3198 1940, Beilstein 21/5 V 492.]

Brand name

Hexa-Betalin (Lilly).
InChI:InChI=1/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H/p-1

58-56-0 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
USP (1587001)  Pyridoxinehydrochloride  United States Pharmacopeia (USP) Reference Standard 58-56-0 1587001-200MG 4,662.45CNY Detail
Supelco (47862)  PyridoxineHydrochloride(B6)  analytical standard 58-56-0 000000000000047862 195.39CNY Detail
Cerilliant (V-018)  Pyridoxine HCl (Vitamin B6) solution  1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material 58-56-0 V-018-1ML 760.50CNY Detail
Sigma-Aldrich (P4100000)  Pyridoxinehydrochloride  European Pharmacopoeia (EP) Reference Standard 58-56-0 P4100000 1,880.19CNY Detail
Sigma-Aldrich (PHR1036)    pharmaceutical secondary standard; traceable to USP, PhEur and BP 58-56-0 PHR1036-500MG 732.19CNY Detail
Alfa Aesar (A12041)  Pyridoxine hydrochloride, 99%    58-56-0 500g 2720.0CNY Detail
Alfa Aesar (A12041)  Pyridoxine hydrochloride, 99%    58-56-0 100g 1082.0CNY Detail
Alfa Aesar (A12041)  Pyridoxine hydrochloride, 99%    58-56-0 25g 343.0CNY Detail
TCI America (P0561)  Pyridoxine Hydrochloride  >98.0%(HPLC)(T) 58-56-0 500g 1,670.00CNY Detail
TCI America (P0561)  Pyridoxine Hydrochloride  >98.0%(HPLC)(T) 58-56-0 100g 590.00CNY Detail
TCI America (P0561)  Pyridoxine Hydrochloride  >98.0%(HPLC)(T) 58-56-0 25g 195.00CNY Detail

58-56-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name pyridoxine hydrochloride

1.2 Other means of identification

Product number -
Other names bonasanit

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:58-56-0 SDS

58-56-0Synthetic route

pyridoxine triacetate
10030-93-0

pyridoxine triacetate

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water for 2h; Heating;98%
With hydrogenchloride; water for 2h; Heating / reflux;72%
5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester
2397-71-9

5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester With sodium tetrahydroborate; iron(II) sulfate; N,N-dimethyl-aniline In tetrahydrofuran for 4h; Reflux;
Stage #2: With hydrogenchloride In tetrahydrofuran at 20℃; Reagent/catalyst; Solvent;
93.4%
4,5-dihydroxymethyl-2-methyl-2-cyclopentenone

4,5-dihydroxymethyl-2-methyl-2-cyclopentenone

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 4,5-dihydroxymethyl-2-methyl-2-cyclopentenone With ozone In methanol; water at -30℃; for 3h;
Stage #2: With ammonia In methanol; water at 20 - 25℃; for 3h;
Stage #3: With hydrogenchloride; pyrographite In ethanol at 55 - 60℃; for 1h; Temperature; Solvent;
92%
2-hydroxymethyl-3-cyano-4-hydroxy-n-butyraldehyde

2-hydroxymethyl-3-cyano-4-hydroxy-n-butyraldehyde

methyl 2-aminopropanoate monohydrochloride
13515-97-4

methyl 2-aminopropanoate monohydrochloride

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 2-hydroxymethyl-3-cyano-4-hydroxy-n-butyraldehyde; methyl 2-aminopropanoate monohydrochloride With sodium methylate In methanol at 30 - 50℃; for 5h; Green chemistry;
Stage #2: With hydrogenchloride In methanol; water for 2h; Temperature; Solvent; Reagent/catalyst; Reflux; Green chemistry;
90.5%
4-methyl-5-dimethyl-tert-butylsiloxyoxazole

4-methyl-5-dimethyl-tert-butylsiloxyoxazole

2-propyl-4,7-dihydro-2H-1,3-dioxepine
4469-34-5

2-propyl-4,7-dihydro-2H-1,3-dioxepine

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 4-methyl-5-dimethyl-tert-butylsiloxyoxazole; 2-propyl-4,7-dihydro-2H-1,3-dioxepine at 115 - 120℃; for 10h;
Stage #2: With water In ethanol at 20℃; for 3h;
Stage #3: With hydrogenchloride In ethanol; water at 20℃; for 2h;
89.5%
Diels-Alder adduct
5205-63-0

Diels-Alder adduct

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: Diels-Alder adduct With hydrogenchloride In ethanol; water at 20℃; for 2h;
Stage #2: In ethanol; water for 2h;
86.05%
C8H13NO4

C8H13NO4

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; pyrographite In ethanol; water at 75 - 78℃; for 3h; Temperature;83.5%
4-methyl-5-triisopropylsiloxyoxazole

4-methyl-5-triisopropylsiloxyoxazole

2-propyl-4,7-dihydro-2H-1,3-dioxepine
4469-34-5

2-propyl-4,7-dihydro-2H-1,3-dioxepine

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 4-methyl-5-triisopropylsiloxyoxazole; 2-propyl-4,7-dihydro-2H-1,3-dioxepine at 115 - 120℃; for 10h;
Stage #2: With water In ethanol at 20℃; for 3h;
Stage #3: With hydrogenchloride In ethanol; water at 20℃; for 2h;
82.7%
2-propyl-4,7-dihydro-2H-1,3-dioxepine
4469-34-5

2-propyl-4,7-dihydro-2H-1,3-dioxepine

4-methyl-5-butoxy1,3-oxazole
24201-52-3

4-methyl-5-butoxy1,3-oxazole

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 2-propyl-4,7-dihydro-2H-1,3-dioxepine; 4-methyl-5-butoxy1,3-oxazole With calcium oxide at 150℃; for 12h; Diels-Alder Cycloaddition;
Stage #2: With hydrogenchloride In ethanol; water at 20 - 60℃; for 12h;
Stage #3: With hydrogenchloride In water for 1h; pH=8; Reagent/catalyst; Reflux;
80%
5-ethoxy-4-methyl-oxazole
5006-20-2

5-ethoxy-4-methyl-oxazole

2-propyl-4,7-dihydro-2H-1,3-dioxepine
4469-34-5

2-propyl-4,7-dihydro-2H-1,3-dioxepine

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride Diels-Alder Cycloaddition;78.5%
3-amino-4,5-bis(aminomethyl)2-methylpyridine trihydrochloride
90330-16-8

3-amino-4,5-bis(aminomethyl)2-methylpyridine trihydrochloride

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite In water at 90℃; for 2h;75%
2-Methyl-3-hydroxy-4,5-bis-(bromomethyl)-pyridine hydrobromide
39984-49-1

2-Methyl-3-hydroxy-4,5-bis-(bromomethyl)-pyridine hydrobromide

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With water; silver(I) chloride for 0.333333h; Heating;68%
Multi-step reaction with 2 steps
1: 2.) AcONa / 1.) DMF, 55 degC, 1 h; 2.) DMF, 85 degC, 2.5 h
2: 98 percent / 2N HCl / H2O / 2 h / Heating
View Scheme
pyridoxamine dihydrochloride
524-36-7

pyridoxamine dihydrochloride

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With sulfuric acid; water; sodium nitrite at 20 - 90℃; for 2h;25%
Thiamine hydrochloride
67-03-8

Thiamine hydrochloride

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With N-Bs In isopropyl alcohol at 25℃; for 0.5h;
L-1-Deoxy<1,1,1-(2)H3,(RS)-5-(2)H1>xylulose
80095-36-9

L-1-Deoxy<1,1,1-(2)H3,(RS)-5-(2)H1>xylulose

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With D-glucose; Escherichia coli B WG2 Mechanism;
3-amino-4-aminomethyl-5-hydroxymethyl-2-methylpyridine dihydrochloride
83537-53-5

3-amino-4-aminomethyl-5-hydroxymethyl-2-methylpyridine dihydrochloride

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With cis-nitrous acid In water at 90℃;
Acetic acid 4-acetoxymethyl-2,5-dimethoxy-2-(1-methoxycarbonylamino-ethyl)-2,5-dihydro-furan-3-ylmethyl ester

Acetic acid 4-acetoxymethyl-2,5-dimethoxy-2-(1-methoxycarbonylamino-ethyl)-2,5-dihydro-furan-3-ylmethyl ester

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water Yield given;
hydrogenchloride
7647-01-0

hydrogenchloride

4,5-bis-aminomethyl-2-methyl-pyridin-3-ol
45996-87-0

4,5-bis-aminomethyl-2-methyl-pyridin-3-ol

aqueous NaNO2

aqueous NaNO2

A

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

B

<5-chloromethyl>-3-hydroxy-2-methyl-<4>pyridyl>-methanol

<5-chloromethyl>-3-hydroxy-2-methyl-<4>pyridyl>-methanol

hydrogenchloride
7647-01-0

hydrogenchloride

4-ethoxymethyl-5-hydroxymethyl-2-methyl-pyridin-3-ol; hydrochloride

4-ethoxymethyl-5-hydroxymethyl-2-methyl-pyridin-3-ol; hydrochloride

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
at 155 - 160℃;
5-amino-6-methylpyridine-3,4-dicarbonitrile
71058-42-9

5-amino-6-methylpyridine-3,4-dicarbonitrile

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 75 percent / conc. HCl, H2 / 5 percent Pd-C / methanol; H2O / 3.5 h / Ambient temperature
2: 75 percent / sodium nitrite, H2SO4 / H2O / 2 h / 90 °C
View Scheme
5-acetoxymethyl-3-amino-2-methylpyridine-4-carbonitrile
83537-57-9

5-acetoxymethyl-3-amino-2-methylpyridine-4-carbonitrile

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 88 percent / 1) conc. HCl, H2; 2) 0.2 N HCl / 1) 5 percent Pd-C / methanol; H2O / 1) 1 h, RT; 2) 1 h, 80 deg C
2: nitrous acid / H2O / 90 °C
View Scheme
3,4-bis(hydroxymethyl)furan
14496-24-3

3,4-bis(hydroxymethyl)furan

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 100 percent / pyridine
2: 57 percent / p-toluenesulfonic acid / 2 h / 0 - 5 °C
3: electrochemical oxidation
4: HCl / H2O
View Scheme
3,4-furan dimethanol diacetate
30614-73-4

3,4-furan dimethanol diacetate

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 57 percent / p-toluenesulfonic acid / 2 h / 0 - 5 °C
2: electrochemical oxidation
3: HCl / H2O
View Scheme
Acetic acid 4-acetoxymethyl-2-(1-methoxycarbonylamino-ethyl)-furan-3-ylmethyl ester
79588-15-1

Acetic acid 4-acetoxymethyl-2-(1-methoxycarbonylamino-ethyl)-furan-3-ylmethyl ester

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: electrochemical oxidation
2: HCl / H2O
View Scheme
1,3-dihydro-6-methyl-7-iodofuro(3,4-c)pyridine
104307-94-0

1,3-dihydro-6-methyl-7-iodofuro(3,4-c)pyridine

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 36 percent / Na, MeOH / CuI2 / various solvent(s) / 16 h / Heating
2: 78 percent / 48percent HBr / 2 h / Heating
3: 68 percent / H2O, AgCl / 0.33 h / Heating
View Scheme
1,3-dihydro-6-methyl-7-methoxyfuro(3,4-c)pyridine
104307-95-1

1,3-dihydro-6-methyl-7-methoxyfuro(3,4-c)pyridine

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 78 percent / 48percent HBr / 2 h / Heating
2: 68 percent / H2O, AgCl / 0.33 h / Heating
View Scheme
1,3-dihydro-6-methyl-7-trimethylstannylfuro(3,4-c)pyridine
104307-93-9

1,3-dihydro-6-methyl-7-trimethylstannylfuro(3,4-c)pyridine

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 99 percent / I2 / CHCl3 / 18 h / Ambient temperature
2: 36 percent / Na, MeOH / CuI2 / various solvent(s) / 16 h / Heating
3: 78 percent / 48percent HBr / 2 h / Heating
4: 68 percent / H2O, AgCl / 0.33 h / Heating
View Scheme
4,5'-O-isobutylidenepyridoxine
1622-67-9

4,5'-O-isobutylidenepyridoxine

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; water under 300.03 Torr; for 2h; Product distribution / selectivity; Heating / reflux;
Stage #1: 4,5'-O-isobutylidenepyridoxine With hydrogenchloride; water In tetrahydrofuran at 60 - 120℃; under 150.015 Torr; for 3h;
Stage #2: With pyrographite In water at 0 - 60℃; Product distribution / selectivity;
3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene
717916-87-5

3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene

A

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

B

4,5'-O-isobutylidenepyridoxine
1622-67-9

4,5'-O-isobutylidenepyridoxine

Conditions
ConditionsYield
Stage #1: 3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene With water; acetic acid In tetrahydrofuran at 60℃; under 760.051 Torr; for 4h;
Stage #2: With hydrogenchloride; water In tetrahydrofuran at 0 - 60℃; for 5h; Product distribution / selectivity;
Stage #1: 3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene With water In tetrahydrofuran at 60℃; under 760.051 Torr; for 4h;
Stage #2: With hydrogenchloride In tetrahydrofuran at 20 - 60℃; for 5h; Product distribution / selectivity;
concentrated H2 SO4

concentrated H2 SO4

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

isopropylidene pyridoxine

isopropylidene pyridoxine

Conditions
ConditionsYield
In acetone100%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

4,5-bis(chloromethyl)-3-hydroxy-2-methylpyridinium chloride
39984-50-4

4,5-bis(chloromethyl)-3-hydroxy-2-methylpyridinium chloride

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide for 0.5h; Reflux; Inert atmosphere;99%
With thionyl chloride In dichloromethane; N,N-dimethyl-formamide for 12h; Reflux;96%
With thionyl chloride; N,N-dimethyl-formamide at 80℃; for 3h;93%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

4-aminobenzene sulfonic acid
121-57-3

4-aminobenzene sulfonic acid

C14H14N2O5S
1122445-21-9

C14H14N2O5S

Conditions
ConditionsYield
Stage #1: pyridoxal hydrochloride With RuCl2(PPh3)2(BAOBEA); dihydrogen peroxide In water at 60℃; for 0.25h;
Stage #2: 4-aminobenzene sulfonic acid In water for 0.0833333h; Reflux;
98.25%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol
1136-52-3

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetone at 20℃;98%
With toluene-4-sulfonic acid In acetone at 20℃; for 23h;96%
With toluene-4-sulfonic acid In acetone at 20℃; for 23h;96%
With toluene-4-sulfonic acid In acetone at 20℃; for 20h; Inert atmosphere;86%
With toluene-4-sulfonic acid In water; acetone for 20h; Inert atmosphere;80%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

acetic anhydride
108-24-7

acetic anhydride

pyridoxine triacetate
10030-93-0

pyridoxine triacetate

Conditions
ConditionsYield
With triethylamine In tert-butyl methyl ether at 50 - 65℃; for 2.5h; Industry scale; Heating / reflux;96%
With pyridine Ambient temperature;57%
With pyridine
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

acetic anhydride
108-24-7

acetic anhydride

2,4-dimethyl-5-acetoxymethylpyridin-3-ol
53580-75-9

2,4-dimethyl-5-acetoxymethylpyridin-3-ol

Conditions
ConditionsYield
With zinc for 2h; Reflux;95%
cobalt(II) chloride hexahydrate

cobalt(II) chloride hexahydrate

Glutamic acid
617-65-2

Glutamic acid

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

Co(2+)*C5HN(CH3)(O)(CH2OH)2(1-)*OOCCH2CH2(NH2)CHCOO(2-)*H(1+)*3H2O=Co{C5HN(CH3)(O)(CH2OH)2}(C5H8NO4)*3H2O

Co(2+)*C5HN(CH3)(O)(CH2OH)2(1-)*OOCCH2CH2(NH2)CHCOO(2-)*H(1+)*3H2O=Co{C5HN(CH3)(O)(CH2OH)2}(C5H8NO4)*3H2O

Conditions
ConditionsYield
With lithium carbonate In water byproducts: CO2; to soln. pyridoxine/water was added equimolar amt. glutamic acid and excess Li2CO3, after evolution CO2 completed addn. equimolar soln. CoCl2/H2O, formation of pink ppt.; ppt. separated, washed (EtOH and ether) until powdery, elem. anal.;94.4%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

3-hydroxy-5-hydroxymethyl-2,4-dimethylpyridinium chloride
148-51-6

3-hydroxy-5-hydroxymethyl-2,4-dimethylpyridinium chloride

Conditions
ConditionsYield
Stage #1: pyridoxal hydrochloride With acetic acid; zinc for 12h; Reflux;
Stage #2: With hydrogenchloride In methanol at 0℃; for 2h;
94%
Stage #1: pyridoxal hydrochloride With acetic acid; zinc for 12h; Reflux;
Stage #2: With hydrogenchloride In methanol; water at 0℃; for 2h;
94%
With acetic acid; zinc for 24h; Reflux;94%
Stage #1: pyridoxal hydrochloride With acetic acid; zinc at 120℃; for 3h;
Stage #2: With hydrogenchloride In methanol at 60℃; for 1h;
93%
Multi-step reaction with 2 steps
1: zinc / 72 h / Reflux
2: hydrogenchloride / water / 8 h / 50 °C
View Scheme
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

4,5-bis-chloromethyl-2-methyl-pyridin-3-ol
102694-13-3

4,5-bis-chloromethyl-2-methyl-pyridin-3-ol

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide for 0.5h; Reflux;93%
With thionyl chloride In N,N-dimethyl-formamide for 0.5h; Inert atmosphere; Reflux;93%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

A

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol
1136-52-3

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

B

1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol
948-00-5

1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol

Conditions
ConditionsYield
With sulfuric acid In dichloromethane for 6h; Heating;A 92%
B n/a
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

A

1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol
948-00-5

1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol

B

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

Conditions
ConditionsYield
With sulfuric acid In dichloromethane for 6h; Heating; Title compound not separated from byproducts;A n/a
B 92%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

acetone
67-64-1

acetone

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride
6953-28-2

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride

Conditions
ConditionsYield
With hydrogenchloride92%
With hydrogenchloride for 2.5h;90.9%
With hydrogenchloride at 20 - 30℃; for 6h;85%
With hydrogenchloride HCl introduction below 10 degC, then -10 degC, overnight;54%
With hydrogenchloride at 0℃; for 2h;27.3 g
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

acetone
67-64-1

acetone

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol
1136-52-3

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

Conditions
ConditionsYield
With thionyl chloride In chloroform at 20℃; for 6h; ketalization;91%
With sulfuric acid at 20℃;65%
With Dess-Martin periodane; toluene-4-sulfonic acid at 20℃; for 20h; Inert atmosphere;63%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

cyclohexanone
108-94-1

cyclohexanone

3,4'-O-cyclohexylidenepyridoxine
4632-05-7

3,4'-O-cyclohexylidenepyridoxine

Conditions
ConditionsYield
With thionyl chloride In chloroform at 20℃; ketalization;90%
With sulfuric acid
Acidic conditions;
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

acetone
67-64-1

acetone

1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol
948-00-5

1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol

Conditions
ConditionsYield
With thionyl chloride In chloroform at 0 - 20℃; for 7h; ketalization;90%
With hydrogenchloride at 3 - 20℃;87%
(i) HCl, (ii) aq. K2CO3; Multistep reaction;
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

acetone
67-64-1

acetone

chlorhydrate d'hydroxy-8 trimethyl-2,2,7 pyrido-<4,5-e>dioxa 1,3-cycloheptane
111422-99-2

chlorhydrate d'hydroxy-8 trimethyl-2,2,7 pyrido-<4,5-e>dioxa 1,3-cycloheptane

Conditions
ConditionsYield
With hydrogenchloride at 0℃; for 1h;88%
Decan-2-one
693-54-9

Decan-2-one

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

5-(hydroxymethyl)-2,8-dimethyl-2-octyl-4H-[1,3]dioxino[4,5-c]pyridine

5-(hydroxymethyl)-2,8-dimethyl-2-octyl-4H-[1,3]dioxino[4,5-c]pyridine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 17h; Reflux; Dean-Stark;87%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

benzoic acid hydrazide
613-94-5

benzoic acid hydrazide

N'-{(3-hydroxyl-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene}benzohydrazide hydrochloride

N'-{(3-hydroxyl-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene}benzohydrazide hydrochloride

Conditions
ConditionsYield
Stage #1: pyridoxal hydrochloride With manganese(IV) oxide; sulfuric acid In water at 60 - 70℃;
Stage #2: benzoic acid hydrazide In water for 0.166667h; Heating;
86%
4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

C50H47NO7

C50H47NO7

Conditions
ConditionsYield
In pyridine; dichloromethane at 20℃; Inert atmosphere;85%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

C40H47NO3Si2

C40H47NO3Si2

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;83%
With triethylamine In tetrahydrofuran for 1.5h; Cooling with ice;67%
pyridoxal hydrochloride
58-56-0

pyridoxal hydrochloride

benzyl bromide
100-39-0

benzyl bromide

[5-(benzyloxy)-4-(hydroxymethyl)-6-methylpyridin-3-yl]methanol
7442-21-9

[5-(benzyloxy)-4-(hydroxymethyl)-6-methylpyridin-3-yl]methanol

Conditions
ConditionsYield
Stage #1: pyridoxal hydrochloride With potassium carbonate In acetonitrile at 90℃; for 1h;
Stage #2: benzyl bromide In acetonitrile for 3h; Reflux;
83%

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields