8-Acetyl-6,11-dimethoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

Base Information

Chemical Name:8-Acetyl-6,11-dimethoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
CAS No.:77422-60-7
Molecular Formula:C22H20 O5
Molecular Weight:364.398
Hs Code.:
NSC Number:164864
DSSTox Substance ID:DTXSID40304236

Synonyms:77422-60-7;NSC164864;DTXSID40304236;8-acetyl-6,11-dimethoxy-7,8,9,10-tetrahydrotetracene-5,12-dione;NSC-164864

Suppliers and Price of 8-Acetyl-6,11-dimethoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 5 raw suppliers

Chemical Property of 8-Acetyl-6,11-dimethoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

Chemical Property:

Vapor Pressure:7.06E-14mmHg at 25°C
Boiling Point:589.6°Cat760mmHg
Flash Point:258.9°C
Density:1.277g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:364.13107373
Heavy Atom Count:27
Complexity:628

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1CCC2=C(C1)C(=C3C(=C2OC)C(=O)C4=CC=CC=C4C3=O)OC

Technology Process of 8-Acetyl-6,11-dimethoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

There total 2 articles about 8-Acetyl-6,11-dimethoxy-7,8,9,10-tetrahydrotetracene-5,12-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85-44-9
phthalic anhydride

: 77422-60-7
8-acetyl-7,8,9,10-tetrahydro-6,11-dimethoxy-5,12-naphthacenedione

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) anhydrous aluminum chloride, sodium chloride, 2.) hydrochloric acid / 1.) 190 deg C, 2 min, 2.) heating, 2 h

2: 82.5 percent / bromine, benzoyl peroxide / tetrachloroethene / 20 h / Heating; Irradiation

3: 69.2 percent / sodium iodide / N,N-dimethyl-acetamide / 0.5 h / 65 - 70 °C

4: 55.6 percent / anhydrous potassium carbonate / dimethylformamide; butan-2-one / 1.5 h / Heating

With hydrogenchloride; aluminium trichloride; Perbenzoic acid; bromine; potassium carbonate; sodium iodide; sodium chloride; In 1,1,2,2-tetrachloroethylene; N,N-dimethyl acetamide; N,N-dimethyl-formamide; butanone;
DOI:10.1021/ja00398a020

Reference yield:

: 85-44-9
phthalic anhydride

: 77422-60-7
8-acetyl-7,8,9,10-tetrahydro-6,11-dimethoxy-5,12-naphthacenedione

Guidance literature:: Multi-step reaction with 5 steps

1: 50 percent / AlCl₃-NaCl / neat (no solvent) / 0.17 h / 180 °C

2: 95 percent / K₂CO₃ / acetone

3: 85 percent / BF₃*(C₂H₅)2O / CHCl₃ / 1.5 h / Ambient temperature

4: CuCl / pyridine / 6 h / Ambient temperature

5: HgCl₂ - HgO / H₂O; acetonitrile / 1 h

With aluminium trichloride; potassium carbonate; sodium chloride; mercury dichloride; mercury(II) oxide; boron trifluoride diethyl etherate; copper(l) chloride; In pyridine; chloroform; water; acetone; acetonitrile;
DOI:10.1016/S0040-4039(00)81613-5