10H-Phenothiazine-10-carboxamide, N,N-bis(2-chloroethyl)-2-methoxy-

Base Information

• Chemical Name: 10H-Phenothiazine-10-carboxamide, N,N-bis(2-chloroethyl)-2-methoxy-
• CAS No.: 65290-91-7
• Molecular Formula: C18H18Cl2N2O2S
• Molecular Weight: 397.3187
• DSSTox Substance ID: DTXSID00215637
• Wikidata: Q83091711
• Mol file: 65290-91-7.mol

Synonyms:BRN 1169191;65290-91-7;10H-Phenothiazine-10-carboxamide, N,N-bis(2-chloroethyl)-2-methoxy-;N,N-Bis(2-chloroethyl)-2-methoxy-10H-phenothiazine-10-carboxamide;C18H18Cl2N2O2S;DTXSID00215637;C18-H18-Cl2-N2-O2-S;LS-105281

Chemical Property of 10H-Phenothiazine-10-carboxamide, N,N-bis(2-chloroethyl)-2-methoxy-

Chemical Property:

• Vapor Pressure: 1.2E-11mmHg at 25°C
• Boiling Point: 538°C at 760 mmHg
• Flash Point: 279.2°C
• Density: 1.363g/cm³
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 396.0466044
• Heavy Atom Count: 25
• Complexity: 451

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC2=C(C=C1)SC3=CC=CC=C3N2C(=O)N(CCCl)CCCl

Technology Process of 10H-Phenothiazine-10-carboxamide, N,N-bis(2-chloroethyl)-2-methoxy-

There total 2 articles about 10H-Phenothiazine-10-carboxamide, N,N-bis(2-chloroethyl)-2-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-phenothiazine-10-carboxylic acid bis-(2-hydroxy-ethyl)-amide (65240-95-1) → 2-methoxy-phenothiazine-10-carboxylic acid bis-(2-chloro-ethyl)-amide (65290-91-7)

Guidance literature:

With thionyl chloride;

Reference yield:

2-methoxy-10H-phenothiazine (1771-18-2) → 2-methoxy-phenothiazine-10-carboxylic acid bis-(2-chloro-ethyl)-amide (65290-91-7)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) , (ii) /BRN= 605315/

2: SOCl₂

With thionyl chloride;

upstream raw materials:

2-methoxy-phenothiazine-10-carboxylic acid bis-(2-hydroxy-ethyl)-amide

2-methoxy-10H-phenothiazine