2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one

Base Information

• Chemical Name: 2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one
• CAS No.: 5801-17-2
• Molecular Formula: C29H20N2O2
• Molecular Weight: 213.117
• DSSTox Substance ID: DTXSID00365308
• Wikidata: Q82149869
• Mol file: 5801-17-2.mol

Synonyms:2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one;2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]fluoren-9-one;ChemDiv1_025418;HMS659D08;DTXSID00365308;NXPKNYBRJICSQH-UHFFFAOYSA-N;STK758127;AKOS001734051;AG-205/11945004;SR-01000520048;SR-01000520048-1

Chemical Property of 2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one

Chemical Property:

• Vapor Pressure: 9.97E-19mmHg at 25°C
• Boiling Point: 687°C at 760 mmHg
• Flash Point: 369.3°C
• Density: 1.274g/cm³
• XLogP3: 6.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 428.152477885
• Heavy Atom Count: 33
• Complexity: 683

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=CC=C3)C4=CC5=C(C=C4)C6=CC=CC=C6C5=O

Technology Process of 2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one

There total 15 articles about 2-[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]-9H-fluoren-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3-phenyl-1-butanol (2722-36-3) → 1-bromo-3-phenylbutane (5801-17-2)

Guidance literature:

With triphenylphosphine dibromide 1:1 addition complex;

DOI:10.1016/j.tet.2006.07.102

Reference yield: 77.0%

4,4,5,5-tetramethyl-2-(3-phenylbutyl)-1,3,2-dioxaborolane → 1-bromo-3-phenylbutane (5801-17-2)

Guidance literature:

4,4,5,5-tetramethyl-2-(3-phenylbutyl)-1,3,2-dioxaborolane; With phenyllithium; In tetrahydrofuran; diethyl ether; at 20 ℃; for 0.5h; Schlenk technique; Inert atmosphere;

With N-Bromosuccinimide; In tetrahydrofuran; diethyl ether; at 20 ℃; for 1h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c9cc03459e

Reference yield: 71.0%

Trifluoro-(3-phenyl-butyl)-silane; compound with GENERIC INORGANIC NEUTRAL COMPONENT → 1-bromo-3-phenylbutane (5801-17-2)

Guidance literature:

With N-Bromosuccinimide; In methanol; for 5h; Ambient temperature;

DOI:10.1246/bcsj.55.255

upstream raw materials:

3-phenyl-1-butanol

1,3-dibromobutane

benzene

α-Methylbenzyllithium

Downstream raw materials:

4-ethyl-3-(3-phenyl-butyl)-1-oxa-3-aza-spiro[4.4]nonan-2-one

1.4-Diphenyl-pentanol

(R/S)-N,N-dimethyl-(3-phenylbutyl)amine

1-Methyl-4-((S)-3-phenyl-butane-1-sulfinyl)-benzene