Methyl 5-(acetylamino)-2-methoxy-4-nitrobenzoate

Base Information

• Chemical Name: Methyl 5-(acetylamino)-2-methoxy-4-nitrobenzoate
• CAS No.: 79893-20-2
• Molecular Formula: C11H12 N2 O6
• Molecular Weight: 268.226
• European Community (EC) Number: 279-334-6
• DSSTox Substance ID: DTXSID701000822
• Nikkaji Number: J320.200C
• Wikidata: Q82994567
• Mol file: 79893-20-2.mol

Synonyms:79893-20-2;Methyl 5-(acetylamino)-2-methoxy-4-nitrobenzoate;EINECS 279-334-6;SCHEMBL12215941;DTXSID701000822;5-Acetylamino-2-methoxy-4-nitrobenzoic acid methyl ester;N-[4-Methoxy-5-(methoxycarbonyl)-2-nitrophenyl]ethanimidic acid

Chemical Property of Methyl 5-(acetylamino)-2-methoxy-4-nitrobenzoate

Chemical Property:

• Vapor Pressure: 7.57E-11mmHg at 25°C
• Boiling Point: 518.3°C at 760 mmHg
• Flash Point: 267.3°C
• Density: 1.366g/cm³
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 268.06953611
• Heavy Atom Count: 19
• Complexity: 367

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=C(C=C(C(=C1)C(=O)OC)OC)[N+](=O)[O-]

Technology Process of Methyl 5-(acetylamino)-2-methoxy-4-nitrobenzoate

There total 1 articles about Methyl 5-(acetylamino)-2-methoxy-4-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 5-(acetylamino)-o-anisate (79893-19-9) → C11H12N2O6 (79893-20-2)

Guidance literature:

With nitric acid; In water; at 0 ℃; for 0.5h;

Reference yield:

C11H12N2O6 (79893-20-2) + methyl iodide (74-88-4) → C11H12N2O6 (735287-35-1)

Guidance literature:

C₁₁H₁₂N₂O₆; methyl iodide; With sodium t-butanolate; In tetrahydrofuran; at 0 - 20 ℃; for 23.5h;

With hydrogenchloride; In water;

upstream raw materials:

methyl 5-(acetylamino)-o-anisate

Downstream raw materials:

C₁₁H₁₂N₂O₆

Refernces

• 1、 -. "VIRAL POLYMERASE INHIBITORS". Page 160. . Retrieved 2010/02/07.