(E)-4-(4-Bromophenyl)-alpha-methylcyclohexanemethylamine hydrochloride

Base Information

Chemical Name:(E)-4-(4-Bromophenyl)-alpha-methylcyclohexanemethylamine hydrochloride
CAS No.:113524-38-2
Molecular Formula:C₁₄H₂₀BrN*ClH
Molecular Weight:318.684
Hs Code.:
DSSTox Substance ID:DTXSID30921092

Synonyms:Mg 16059;trans-1-(4-(4-Bromofenil)cicloesil)etilammina cloridrato [Italian];(E)-4-(4-Bromophenyl)-alpha-methylcyclohexanemethylamine hydrochloride;Cyclohexanemethanamine, 4-(4-bromophenyl)-alpha-methyl-, hydrochloride, trans-;Cyclohexanemethylamine, 4-(4-bromophenyl)-alpha-methyl-, hydrochloride, (E)-;113524-38-2;trans-1-(4-(4-Bromofenil)cicloesil)etilammina cloridrato;C14H20BrN.ClH;C14-H20-Br-N.Cl-H;DTXSID30921092;LS-56927;1-[4-(4-Bromophenyl)cyclohexyl]ethan-1-amine--hydrogen chloride (1/1)

Suppliers and Price of (E)-4-(4-Bromophenyl)-alpha-methylcyclohexanemethylamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of (E)-4-(4-Bromophenyl)-alpha-methylcyclohexanemethylamine hydrochloride

Chemical Property:

Vapor Pressure:3.7E-05mmHg at 25°C
Boiling Point:353°C at 760 mmHg
Flash Point:167.3°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:317.05459
Heavy Atom Count:17
Complexity:203

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1CCC(CC1)C2=CC=C(C=C2)Br)N.Cl

Technology Process of (E)-4-(4-Bromophenyl)-alpha-methylcyclohexanemethylamine hydrochloride

There total 4 articles about (E)-4-(4-Bromophenyl)-alpha-methylcyclohexanemethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21060-31-1
trans-1-(4-Phenylcyclohexyl)-1-ethanon

: 113524-38-2
trans-1-<4-(4-bromofenil)cicloesil>etilammina cloridrato

Guidance literature:: Multi-step reaction with 4 steps

1: 72 percent / 90percent nitric acid / CHCl₃ / 1.5 h / -30 °C

2: 80 percent / hydrogen / 10percent Pd/C / ethyl acetate / Ambient temperature

3: 35 percent / copper bromide, butyl nitrite / acetonitrile / 1.) 50 deg C, 30 min; 2.) 1 h, r.t.

4: 1.) 99percent formic acid; 2.) conc. hydrochloric acid / 1.) formamide, 180 deg C, 20 h; 2.) 5 h, reflux

With hydrogenchloride; formic acid; copper bromide; n-Butyl nitrite; hydrogen; nitric acid; palladium on activated charcoal; In chloroform; ethyl acetate; acetonitrile;

Reference yield:

: 113524-41-7
trans-1-acetil-4-(4-nitrofenil)cicloesano

: 113524-38-2
trans-1-<4-(4-bromofenil)cicloesil>etilammina cloridrato

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / hydrogen / 10percent Pd/C / ethyl acetate / Ambient temperature

2: 35 percent / copper bromide, butyl nitrite / acetonitrile / 1.) 50 deg C, 30 min; 2.) 1 h, r.t.

3: 1.) 99percent formic acid; 2.) conc. hydrochloric acid / 1.) formamide, 180 deg C, 20 h; 2.) 5 h, reflux

With hydrogenchloride; formic acid; copper bromide; n-Butyl nitrite; hydrogen; palladium on activated charcoal; In ethyl acetate; acetonitrile;

Reference yield:

: 113524-43-9
trans-1-acetil-4-(4-amminofenil)cicloesano

: 113524-38-2
trans-1-<4-(4-bromofenil)cicloesil>etilammina cloridrato

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / copper bromide, butyl nitrite / acetonitrile / 1.) 50 deg C, 30 min; 2.) 1 h, r.t.

2: 1.) 99percent formic acid; 2.) conc. hydrochloric acid / 1.) formamide, 180 deg C, 20 h; 2.) 5 h, reflux

With hydrogenchloride; formic acid; copper bromide; n-Butyl nitrite; In acetonitrile;