N-ALLYLMORPHOLINE

Base Information

• Chemical Name: N-ALLYLMORPHOLINE
• CAS No.: 696-57-1
• Molecular Formula: C7H13NO
• Molecular Weight: 127.186
• Hs Code.: 2934999090
• Mol file: 696-57-1.mol

Synonyms:Morpholine,4-(2-propenyl)- (9CI);Morpholine, 4-allyl- (7CI,8CI);4-(2-Propenyl)morpholine;4-Allylmorpholine;N-Allylmorpholine;4-(prop-2-en-1-yl)morpholine;4-(Prop-2-en-1-yl)morpholin;4-Allylmorpholine;morpholine, 4-(2-propen-1-yl)-;N-Allyl morpholine;

Chemical Property of N-ALLYLMORPHOLINE

Chemical Property:

• Vapor Pressure: 2.56mmHg at 25°C
• Refractive Index: 1.454
• Boiling Point: 158.9 °C at 760 mmHg
• Flash Point: 42.7 °C
• PSA: 12.47000
• Density: 0.923 g/cm³
• LogP: 0.44250

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Allylmorpholine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-ALLYLMORPHOLINE

There total 8 articles about N-ALLYLMORPHOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

morpholine (110-91-8,99108-56-2) + 1-(2-allyloxyphenyl)-1-phenylhept-2-yn-1-ol (934569-84-3) + carbon monoxide (201230-82-2) → N-allylmorpholine (696-57-1) + 1-(morpholin-4-yl)-2-(3-phenylbenzofuran-2-yl)hexan-1-one

Guidance literature:

With triphenylphosphine; potassium iodide; palladium(II) iodide; In methanol; at 100 ℃; for 15h; under 22801.5 Torr;

DOI:10.1021/jo701956k

Reference yield: 66.0%

2-(1-Hydroxy-3-phenyl-2-propynyl)-(2-propenyloxy)benzene (845464-90-6) + morpholine (110-91-8,99108-56-2) + carbon monoxide (201230-82-2) → N-allylmorpholine (696-57-1) + 2-(benzofuran-2-yl)-1-(morpholin-4-yl)-2-phenylethanone + 1-(o-hydroxyphenyl)-3-phenylpropargylic alcohol (109365-86-8)

Guidance literature:

With triphenylphosphine; potassium iodide; palladium(II) iodide; In methanol; at 100 ℃; for 15h; under 22801.5 Torr;

DOI:10.1021/jo701956k

Reference yield: 65.0%

morpholine (110-91-8,99108-56-2) + 1-(2-allyloxy-5-methoxyphenyl)-3-phenylprop-2-yn-1-ol (934569-92-3) + carbon monoxide (201230-82-2) → N-allylmorpholine (696-57-1) + 2-(5-methoxybenzofuran-2-yl)-1-(morpholin-4-yl)-2-phenylethanone

Guidance literature:

With triphenylphosphine; potassium iodide; palladium(II) iodide; In methanol; at 100 ℃; for 15h; under 22801.5 Torr;

DOI:10.1021/jo701956k

upstream raw materials:

morpholine

1,2-propanediene

allyl morpholine-4-carboxylate

1-allyl-2,4,6-triphenylpyridin-1-ium tetrafluoroborate salt

Downstream raw materials:

C₂₄H₄₄N₂O₂Si₂

2-morpholinopropane-1,3-diyl dibenzoate

3-morpholinopropane-1,2-diyl dibenzoate

N-allyl-N-methyl-4-toluene sulphonamide

Refernces

AMINATION OF DIENE HYDROCARBONS. 1. PREPARATION OF N-(2,3-DIMETHYLENEBUTYL)MORPHOLINE BY TELOMERIZATION OF PROPANE

10.1007/BF00952390

The study investigates the telomerization of propadiene by morpholine, using a binary catalytic system composed of PdCl2 and triphenylphosphine. The primary product formed is N-(2,3-dimethylenebutyl)morpholine, with a yield of approximately 49.5%, and a small amount of allylmorpholine is also produced. Nonaminated propadiene oligomers are observed as by-products. The addition of a reducing agent, NaBH4, enhances the catalytic activity without significantly altering the selectivity. However, the introduction of CF3COOH, which is used as an activating additive in the amination of butadiene, decreases the yield and shifts the selectivity towards the formation of heavier products. The study also explores the effects of varying the initial concentration of morpholine and the ratio of propadiene to morpholine, finding that these factors significantly influence the reaction rate and the isomeric composition of the products. The presence of conjugated double bonds in the hydrocarbon substituent of the product allows for further conversion into high-molecular-weight products.