2-Chloro-6-methoxy-8-nitroquinoline

Base Information

Chemical Name:2-Chloro-6-methoxy-8-nitroquinoline
CAS No.:52824-29-0
Molecular Formula:C10H7ClN2O3
Molecular Weight:238.6272
Hs Code.:
NSC Number:115168
DSSTox Substance ID:DTXSID70297304
Wikidata:Q82038330
Mol file:52824-29-0.mol

Synonyms:2-Chloro-6-methoxy-8-nitroquinoline;52824-29-0;NSC115168;SCHEMBL11072978;DTXSID70297304;NSC-115168

Suppliers and Price of 2-Chloro-6-methoxy-8-nitroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Chloro-6-methoxy-8-nitroquinoline

Chemical Property:

Vapor Pressure:3.17E-06mmHg at 25°C
Boiling Point:399.4°C at 760 mmHg
Flash Point:195.3°C
Density:1.45g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:238.0145198
Heavy Atom Count:16
Complexity:271

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C2C(=C1)C=CC(=N2)Cl)[N+](=O)[O-]

Technology Process of 2-Chloro-6-methoxy-8-nitroquinoline

There total 4 articles about 2-Chloro-6-methoxy-8-nitroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52824-28-9
1-methyl-6-methoxy-8-nitroquinoline-2-one

: 52824-29-0
2-chloro-6-methoxy-8-nitro-quinoline

Guidance literature:: With phosphorus pentachloride; at 170 - 185 ℃;
DOI:10.1021/ja01212a050

Reference yield:

: 85-81-4
6-methoxy-8-nitroquinoline

: 52824-29-0
2-chloro-6-methoxy-8-nitro-quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: Behandeln des Reaktionsgemisches mit Wasser und Kaliumjodid

2: aqueous hydrogen peroxide; aq.-ethanolic KOH-solution

3: phosphorus (V)-chloride / 170 - 185 °C

With potassium hydroxide; phosphorus pentachloride; dihydrogen peroxide;
DOI:10.1021/ja01212a050

Reference yield:

: 52824-44-9
6-methoxy-1-methyl-8-nitro-quinolinium; iodide

: 52824-29-0
2-chloro-6-methoxy-8-nitro-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: aqueous hydrogen peroxide; aq.-ethanolic KOH-solution

2: phosphorus (V)-chloride / 170 - 185 °C

With potassium hydroxide; phosphorus pentachloride; dihydrogen peroxide;
DOI:10.1021/ja01212a050