6-METHOXY-8-NITROQUINOLINE

Base Information

Chemical Name:6-METHOXY-8-NITROQUINOLINE
CAS No.:85-81-4
Molecular Formula:C10H8 N2 O3
Molecular Weight:204.185
Hs Code.:29334900
European Community (EC) Number:201-633-7
NSC Number:1883
UNII:ATS412O1XO
DSSTox Substance ID:DTXSID50234050
Nikkaji Number:J797H
Wikidata:Q27274117
ChEMBL ID:CHEMBL166980
Mol file:85-81-4.mol

Synonyms:6-Methoxy-8-nitroquinoline;8-Nitro-6-methoxyquinoline; NSC 1883

Suppliers and Price of 6-METHOXY-8-NITROQUINOLINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Methoxy-8-nitroquinoline
500mg
$ 50.00

TCI Chemical
6-Methoxy-8-nitroquinoline >98.0%(GC)
5g
$ 106.00

TCI Chemical
6-Methoxy-8-nitroquinoline >98.0%(GC)
25g
$ 369.00

SynQuest Laboratories
6-Methoxy-8-nitroquinoline
100 g
$ 453.00

SynQuest Laboratories
6-Methoxy-8-nitroquinoline
25 g
$ 152.00

SynQuest Laboratories
6-Methoxy-8-nitroquinoline
10 g
$ 77.00

Sigma-Aldrich
6-Methoxy-8-nitroquinoline 99%
1g
$ 68.60

Matrix Scientific
6-Methoxy-8-nitroquinoline
1g
$ 129.00

Matrix Scientific
6-Methoxy-8-nitroquinoline
10g
$ 675.00

Frontier Specialty Chemicals
6-Methoxy-8-nitroquinoline 98%
1g
$ 80.00

Total 59 raw suppliers

Chemical Property of 6-METHOXY-8-NITROQUINOLINE

Chemical Property:

Appearance/Colour:YELLOW CRYSTALLINE POWDER
Vapor Pressure:1.97E-05mmHg at 25°C
Melting Point:158-160 °C(lit.)
Refractive Index:1.5910 (estimate)
Boiling Point:373.1°C at 760 mmHg
PKA:1.25±0.20(Predicted)
Flash Point:179.4°C
PSA：67.94000
Density:1.337g/cm³
LogP:2.67480
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:204.05349212
Heavy Atom Count:15
Complexity:241

Purity/Quality:

99% ^*data from raw suppliers

6-Methoxy-8-nitroquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 20/21/22-36/37/38-40
Safety Statements: 26-27-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C2C(=C1)C=CC=N2)[N+](=O)[O-]
Uses 6-Methoxy-8-nitroquinoline is used in treating and preventing pancreatic cancer. Also, used in preparation of Quinoline derivatives as antiparasitic agents useful in the prophylaxis and treatment of malaria and parasitic diseases.

Technology Process of 6-METHOXY-8-NITROQUINOLINE

There total 9 articles about 6-METHOXY-8-NITROQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 56-81-5,25618-55-7,64333-26-2,8013-25-0
glycerol

: 96-96-8
4-methoxy-2-nitroaniline

: 85-81-4
6-methoxy-8-nitroquinoline

Guidance literature:: glycerol; 4-methoxy-2-nitroaniline; With sodium iodide; at 20 ℃; for 0.0833333h;

With sulfuric acid; for 0.166667h; Cooling with ice;

at 140 ℃; for 2h;
DOI:10.1021/acs.joc.9b00942