6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hexanoic acid

Base Information

• Chemical Name: 6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hexanoic acid
• CAS No.: 88574-06-5
• Molecular Formula: C21H23NO4
• Molecular Weight: 353.418
• Hs Code.: 2924 29 70
• European Community (EC) Number: 627-935-2
• DSSTox Substance ID: DTXSID401008239
• Nikkaji Number: J957.086A
• Wikidata: Q72477858
• ChEMBL ID: CHEMBL1320484
• Mol file: 88574-06-5.mol

Synonyms:88574-06-5;FMOC-6-AMINOHEXANOIC ACID;Fmoc-6-Ahx-OH;Fmoc-|A-Acp-OH;N-Fmoc-6-aminohexanoic acid;6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hexanoic acid;6-(Fmoc-amino)hexanoic acid;6-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic Acid;6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}hexanoic acid;Fmoc-6-Aminocaproic Acid;Fmoc-epsilon-aminocaproic acid;MFCD00077045;Fmoc-epsilon-Acp-OH;Hexanoic acid, 6-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-;Fmoc-LC-OH;Fmoc-epsilonAhx-OH;Fmoc-6-aminohexanoic acid;6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid;6-{{[(9H-Fluoren-9-yl)methoxy]carbonyl}amino}hexanoic Acid;Fmoc-epsilon- Aminocaproic acid;Fmoc-Imicro-Acp-OH;Fmoc-epsilon-Ahx-OH;Fmoc-?-Acp-OH;Fmoc-Acp(6)-OH;Fmoc--aminocaproic acid;N-Fmoc-6-aminocaproic acid;SCHEMBL25143;MLS001197251;CHEMBL1320484;FPCPONSZWYDXRD-UHFFFAOYSA-N;DTXSID401008239;HMS2883B03;STK082390;AKOS001623857;CS-W009405;DS-8037;BP-28254;SMR000555403;SY017587;Fmoc-6-Ahx-OH, >=97.0% (HPLC);AM20041325;FT-0688934;EN300-650271;I10487;A842712;SR-01000081603;Fmoc-Ahx-OH;J-300330;SR-01000081603-1;6-(9H-Fluoren-9-ylmethoxycarbonylamino)-hexanoic acid;6-(9H-Fluorene-9-ylmethoxycarbonylamino)hexanoic acid;Z1123719981;6-(((9H-fluoren-9-yl)methoxy)carbonylamino)hexanoic acid;N-(9-Fluorenylmethyloxycarbonyl)-epsilon-amino-capronic acid;6-({[(9H-Fluoren-9-yl)methoxy](hydroxy)methylidene}amino)hexanoic acid;6-amino-2-(9H-fluoren-9-ylmethoxycarbonyl)hexanoic acid;Fmoc-6-Aminohexanoic acid

Chemical Property of 6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hexanoic acid

Chemical Property:

• Vapor Pressure: 2.02E-14mmHg at 25°C
• Melting Point: 114 °C
• Refractive Index: 1.585
• Boiling Point: 582.7 °C at 760 mmHg
• PKA: 4.75±0.10(Predicted)
• Flash Point: 306.2 °C
• PSA: 75.63000
• Density: 1.21 g/cm³
• LogP: 4.56100
• Storage Temp.: 2-8°C
• Water Solubility.: Soluble in 1% acetic acid, water and 1mmol in 2mL DMF clearly soluble.
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 353.16270821
• Heavy Atom Count: 26
• Complexity: 459

Purity/Quality:

99% ^*data from raw suppliers

Fmoc-6-aminohexanoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCCCCC(=O)O
• Description: Fmoc-6-aminohexanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-6-aminohexanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
• Uses: Fmoc-6-aminohexanoic acid, is an amino acid derivative used in chemical synthesis and peptide chemistry.