4-(Benzenesulfonyl)-N-[(4-chlorophenyl)methyl]-2-(thiophen-2-yl)-1,3-oxazol-5-amine

Base Information

Chemical Name:4-(Benzenesulfonyl)-N-[(4-chlorophenyl)methyl]-2-(thiophen-2-yl)-1,3-oxazol-5-amine
CAS No.:7065-28-3
Molecular Formula:C₁₁H₁₄O
Molecular Weight:162.232
Hs Code.:
DSSTox Substance ID:DTXSID00990876
Wikidata:Q82980517

Synonyms:7065-28-3;DTXSID00990876;AKOS002780764;4-(Benzenesulfonyl)-N-[(4-chlorophenyl)methyl]-2-(thiophen-2-yl)-1,3-oxazol-5-amine

Suppliers and Price of 4-(Benzenesulfonyl)-N-[(4-chlorophenyl)methyl]-2-(thiophen-2-yl)-1,3-oxazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-(Benzenesulfonyl)-N-[(4-chlorophenyl)methyl]-2-(thiophen-2-yl)-1,3-oxazol-5-amine

Chemical Property:

Vapor Pressure:1.08E-16mmHg at 25°C
Boiling Point:648.3°Cat760mmHg
Flash Point:345.9°C
Density:1.433g/cm³
XLogP3:5.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:430.0212624
Heavy Atom Count:28
Complexity:601

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)C2=C(OC(=N2)C3=CC=CS3)NCC4=CC=C(C=C4)Cl

Technology Process of 4-(Benzenesulfonyl)-N-[(4-chlorophenyl)methyl]-2-(thiophen-2-yl)-1,3-oxazol-5-amine

There total 11 articles about 4-(Benzenesulfonyl)-N-[(4-chlorophenyl)methyl]-2-(thiophen-2-yl)-1,3-oxazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 2550-26-7
4-Phenyl-2-butanone

: 1774-47-6
trimethylsulfoxonium iodide

: 7065-28-3,130284-36-5
2-methyl-2-phenethyloxirane

Guidance literature:: With potassium tert-butylate; In dimethyl sulfoxide; at 20 ℃; Inert atmosphere;
DOI:10.1021/ol101406k

Reference yield: 89.0%

: 6683-51-8
2-methyl-4-phenyl-1-butene

: 7065-28-3,130284-36-5
2-methyl-2-phenethyloxirane

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; Schlenk technique; Inert atmosphere;
DOI:10.1021/ja400325w

Reference yield: 89.0%

: 2550-26-7
4-Phenyl-2-butanone

: 333-27-7
methyl trifluoromethanesulfonate

: 7065-28-3,130284-36-5
2-methyl-2-phenethyloxirane

Guidance literature:: 4-Phenyl-2-butanone; methyl trifluoromethanesulfonate; With thiophene; styrene; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; In dichloromethane; at 20 ℃; for 0.416667h; Inert atmosphere;

With 1-tert-butyl-2,2,4,4,4-pentakis(dimethylamino)-2Λ⁵,4Λ⁵-catenadi(phosphazene); In tetrahydrofuran; dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1002/adsc.201000255