2-[[4-[(2,4-diamino-5-oxo-8H-pyrido[2,3-d]pyrimidin-6-yl)methylsulfanyl]benzoyl]amino]pentanedioic acid

Base Information

Chemical Name:2-[[4-[(2,4-diamino-5-oxo-8H-pyrido[2,3-d]pyrimidin-6-yl)methylsulfanyl]benzoyl]amino]pentanedioic acid
CAS No.:74332-04-0
Molecular Formula:C20H20N6O6S
Molecular Weight:472.4744
Hs Code.:
NSC Number:344242
DSSTox Substance ID:DTXSID60419553

Synonyms:NSC344242;74332-04-0;DTXSID60419553;NSC-344242

Suppliers and Price of 2-[[4-[(2,4-diamino-5-oxo-8H-pyrido[2,3-d]pyrimidin-6-yl)methylsulfanyl]benzoyl]amino]pentanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 2-[[4-[(2,4-diamino-5-oxo-8H-pyrido[2,3-d]pyrimidin-6-yl)methylsulfanyl]benzoyl]amino]pentanedioic acid

Chemical Property:

Density:1.62g/cm³
XLogP3:0.8
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:9
Exact Mass:472.11650355
Heavy Atom Count:33
Complexity:802

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)SCC2=CNC3=NC(=NC(=C3C2=O)N)N

Technology Process of 2-[[4-[(2,4-diamino-5-oxo-8H-pyrido[2,3-d]pyrimidin-6-yl)methylsulfanyl]benzoyl]amino]pentanedioic acid

There total 3 articles about 2-[[4-[(2,4-diamino-5-oxo-8H-pyrido[2,3-d]pyrimidin-6-yl)methylsulfanyl]benzoyl]amino]pentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 74346-18-2
Diethyl N-pyrimidin-6-yl)methyl>thio>benzoyl>-L-glutamate

: 74332-04-0
N-pyrimidin-6-yl)methyl>thio>benzoyl>-L-glutamic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 48h; Ambient temperature;
DOI:10.1021/jo01307a004

Reference yield:

: 74332-06-2
2,4-Diamino-6-(hydroxymethyl)-5-oxopyrido<2,3-d>pyrimidine

: 74332-04-0
N-pyrimidin-6-yl)methyl>thio>benzoyl>-L-glutamic acid

Guidance literature:: Multi-step reaction with 3 steps

1: gaseous HBr / dioxane

2: dimethylformamide / 6 h / Ambient temperature

3: 57 percent / 1 N NaOH / ethanol / 48 h / Ambient temperature

With sodium hydroxide; hydrogen bromide; In 1,4-dioxane; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jo01307a004

Reference yield:

: 74332-07-3
2,4-Diamino-6-bromomethyl-8H-pyrido[2,3-d]pyrimidin-5-one

: 74332-04-0
N-pyrimidin-6-yl)methyl>thio>benzoyl>-L-glutamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / 6 h / Ambient temperature

2: 57 percent / 1 N NaOH / ethanol / 48 h / Ambient temperature

With sodium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jo01307a004