Flindersiamine

Base Information

Chemical Name:Flindersiamine
CAS No.:522-06-5
Molecular Formula:C₁₄H₁₁NO₅
Molecular Weight:273.245
Hs Code.:2934999090
NSC Number:284684
UNII:6Q8RKP2039
DSSTox Substance ID:DTXSID40200229
Nikkaji Number:J122.156F
Wikidata:Q27106652
Metabolomics Workbench ID:67828
ChEMBL ID:CHEMBL503519
Mol file:522-06-5.mol

Synonyms:flindersiamine

Suppliers and Price of Flindersiamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
FLINDERSIAMINE 95.00%
5MG
$ 497.77

Total 9 raw suppliers

Chemical Property of Flindersiamine

Chemical Property:

Vapor Pressure:2.56E-07mmHg at 25°C
Boiling Point:433.6°Cat760mmHg
Flash Point:216°C
PSA：62.95000
Density:1.416g/cm³
LogP:2.72690
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:273.06372245
Heavy Atom Count:20
Complexity:368

Purity/Quality:

98%min ^*data from raw suppliers

FLINDERSIAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C2C=COC2=NC3=C(C4=C(C=C31)OCO4)OC

Technology Process of Flindersiamine

There total 2 articles about Flindersiamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 94521-11-6
9-chloro-4-methoxy-[1,3]dioxolo[4,5-g]furo[2,3-b]quinoline

: 124-41-4
sodium methylate

: 522-06-5
flindersiamine

Guidance literature:: In methanol;

Reference yield:

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 82202-82-2
tecleine

: 522-06-5
flindersiamine

Guidance literature:: In ethyl acetate;

Reference yield:

: 522-06-5
flindersiamine

: 8-methoxy-N-phenyl-1,3-dioxolo[4,5-g]furo[2,3-b]quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: phosphorus tribromide; N,N-dimethyl-formamide / 1.5 h / 60 °C

2: palladium diacetate; potassium phosphate; bis[2-(diphenylphosphino)phenyl] ether / neat (no solvent) / 18 h / 100 - 120 °C / Inert atmosphere; Green chemistry

With potassium phosphate; palladium diacetate; phosphorus tribromide; N,N-dimethyl-formamide; bis[2-(diphenylphosphino)phenyl] ether; In neat (no solvent); 2: |Buchwald-Hartwig Coupling;
DOI:10.1002/cmdc.202100784