2-Morpholin-4-yl-1-phenylethylamine

Base Information

• Chemical Name: 2-Morpholin-4-yl-1-phenylethylamine
• CAS No.: 38060-08-1
• Molecular Formula: C12H18N2O
• Molecular Weight: 206.288
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID50384640
• ChEMBL ID: CHEMBL203233
• Mol file: 38060-08-1.mol

Synonyms:38060-08-1;2-Morpholin-4-yl-1-phenylethylamine;2-morpholino-1-phenylethanamine;2-morpholin-4-yl-1-phenylethanamine;2-(Morpholin-4-Yl)-1-Phenylethan-1-Amine;2-Morpholin-4-yl-1-phenyl-ethylamine;2-morpholino-1-phenylethan-1-amine;a-Phenyl-4-morpholineethanamine;CHEMBL203233;SCHEMBL2554004;2-Morpholin-4-ylphenethyl amine;DTXSID50384640;CLAGARRWBBUZDR-UHFFFAOYSA-N;HMS1704I02;AR3539;MFCD01862532;AKOS000256879;AKOS016037567;PS-3605;2-(Morpholin-4-yl)-1-phenylethylamine;CS-0171283;FT-0677697;EN300-14666;2-morpholin-4-yl-1-phenylethylamine, AldrichCPR;BRD-A82277173-001-01-1

Chemical Property of 2-Morpholin-4-yl-1-phenylethylamine

Chemical Property:

• Vapor Pressure: 0.00027mmHg at 25°C
• Refractive Index: 1.55
• Boiling Point: 322.9 °C at 760 mmHg
• PKA: 10.29±0.10(Predicted)
• Flash Point: 149.1 °C
• PSA: 38.49000
• Density: 1.078 g/cm³
• LogP: 1.65680
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 206.141913202
• Heavy Atom Count: 15
• Complexity: 175

Purity/Quality:

98%Min ^*data from raw suppliers

2-Morpholin-4-yl-1-phenylethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C,Xi
• Hazard Codes: C,Xi,T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1CC(C2=CC=CC=C2)N

Technology Process of 2-Morpholin-4-yl-1-phenylethylamine

There total 3 articles about 2-Morpholin-4-yl-1-phenylethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-1-morpholin-4-yl-2-phenylethanone (877125-77-4) → 2-(morpholin-4-yl)-1-phenylethan-1-amine (38060-08-1)

Guidance literature:

2-amino-1-morpholin-4-yl-2-phenylethanone; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 2h; Heating / reflux;

With water; sodium sulfate; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h;

Reference yield:

syn-α-Morpholinoacetophenone oxime (15437-09-9,91557-33-4) → 2-(morpholin-4-yl)-1-phenylethan-1-amine (38060-08-1)

Guidance literature:

With ethanol; sodium;

DOI:10.1021/ja01234a006

Reference yield:

→ 2-(morpholin-4-yl)-1-phenylethan-1-amine (38060-08-1)

Guidance literature:

Entspr. 2'-Oximoderivat von 2 und Na;

DOI:10.1016/S0040-4020(01)92505-0

upstream raw materials:

syn-α-Morpholinoacetophenone oxime

2-amino-1-morpholin-4-yl-2-phenylethanone

Downstream raw materials:

2-cyano-4-(cyclohexylmethylamino)pyrimidine-5-carboxylic acid (2-morpholin-4-yl-1-phenylethyl)amide

C₃₀H₃₆F₃N₅O₂

Refernces