2-(4-Morpholinyl)-1-phenylethanone hydrochloride

Base Information

• Chemical Name: 2-(4-Morpholinyl)-1-phenylethanone hydrochloride
• CAS No.: 66502-26-9
• Molecular Formula: C12H15NO2
• Molecular Weight: 205.253
• NSC Number: 45276,23627,20764
• Mol file: 66502-26-9.mol

Synonyms:66502-26-9;2-(4-morpholinyl)-1-phenylethanone hydrochloride;NSC20764;NSC23627;NSC45276;NSC-20764;NSC-23627;NSC-45276;AKOS024395568;MCULE-6672614839

Chemical Property of 2-(4-Morpholinyl)-1-phenylethanone hydrochloride

Chemical Property:

• Vapor Pressure: 0.000168mmHg at 25°C
• Boiling Point: 330.3°C at 760 mmHg
• Flash Point: 153.5°C
• Density: 1.106g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 241.0869564
• Heavy Atom Count: 16
• Complexity: 206

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1CC(=O)C2=CC=CC=C2.Cl

Technology Process of 2-(4-Morpholinyl)-1-phenylethanone hydrochloride

There total 1 articles about 2-(4-Morpholinyl)-1-phenylethanone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-morpholino-1-phenyl-ethanone; hydrochloride (66502-26-9)

Guidance literature:

Reference yield: 87.0%

potassium cyanide (151-50-8) + 2-morpholino-1-phenyl-ethanone; hydrochloride (66502-26-9) → 5-morpholin-4-ylmethyl-5-phenyl-imidazolidine-2,4-dione (66502-22-5)

Guidance literature:

With ammonium carbonate; In ethanol; water; at 60 - 65 ℃; for 48h;

Reference yield:

2-morpholino-1-phenyl-ethanone; hydrochloride (66502-26-9) + o-aminobenzaldehyde (529-23-7) → 3-morpholino-2-phenyl-quinoline (5443-61-8)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01580a025

Downstream raw materials:

5-morpholin-4-ylmethyl-5-phenyl-imidazolidine-2,4-dione

2-morpholino-1-phenylethanol

3-morpholino-2-phenyl-quinoline

2-morpholino-1-phenyl-ethanone-phenylhydrazone