Ethane-1,1,2,2-tetracarboxylic Acid

Base Information

• Chemical Name: Ethane-1,1,2,2-tetracarboxylic Acid
• CAS No.: 4378-76-1
• Molecular Formula: C6H6O8
• Molecular Weight: 206.109
• Hs Code.: 2917190090
• DSSTox Substance ID: DTXSID20424168
• Nikkaji Number: J1.091.236I
• Wikidata: Q82236629
• Mol file: 4378-76-1.mol

Synonyms:4378-76-1;Ethane-1,1,2,2-tetracarboxylic Acid;1,1,2,2-Ethanetetracarboxylic acid;dicarboxy-succinic acid;2,2'-Bi[malonic acid];SCHEMBL29255;DTXSID20424168

Chemical Property of Ethane-1,1,2,2-tetracarboxylic Acid

Chemical Property:

• PSA: 149.20000
• LogP: -1.44280
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 5
• Exact Mass: 206.00626715
• Heavy Atom Count: 14
• Complexity: 234

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)O)C(=O)O)(C(=O)O)C(=O)O

Technology Process of Ethane-1,1,2,2-tetracarboxylic Acid

There total 5 articles about Ethane-1,1,2,2-tetracarboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

malonic acid (141-82-2) → acetonedicarboxylic acid (473-90-5) + 1,1,2,2-Ethane-tetracarboxylic acid (4378-76-1) + oxalic acid (144-62-7,97993-78-7) + monomalonyl malonate (173040-78-3)

Guidance literature:

With sodium bromate; sulfuric acid; cerium (IV) sulfate; In water; at 22 ℃; Further Variations:; Reagents; Temperatures; reaction time; Product distribution; anaerobic;

DOI:10.1039/b004903o

Reference yield:

malonic acid (141-82-2) → tartronic acid (80-69-3) + acetonedicarboxylic acid (473-90-5) + 1,1,2,2-Ethane-tetracarboxylic acid (4378-76-1) + dicarboxymethyl (3247-02-7) + peroxymalonyl radical

Guidance literature:

With 4H₃N*CeH₄O₁₆S₄; sulfuric acid; at 25 ℃; Rate constant; Mechanism; deuterated analog;

DOI:10.1021/ja00128a033

Reference yield:

malonic acid (141-82-2) → tartronic acid (80-69-3) + 1,1,2,2-Ethane-tetracarboxylic acid (4378-76-1) + Glyoxilic acid (298-12-4)

Guidance literature:

With cerium (IV) sulfate; sulfuric acid; In water; Mechanism; Rate constant; Ambient temperature;

DOI:10.1021/jp964009s

upstream raw materials:

malonic acid

Downstream raw materials:

succinic acid

carbon dioxide

(+/-)-cis-tetrahydro-furo[3,4-c]furan-1,4-dione