1,1-Dibromo-2-2-diphenylcyclopropane

Base Information

• Chemical Name: 1,1-Dibromo-2-2-diphenylcyclopropane
• CAS No.: 17343-74-7
• Molecular Formula: C15H12 Br2
• Molecular Weight: 352.068
• Hs Code.: 2903999090
• Mol file: 17343-74-7.mol

Synonyms:Cyclopropane,1,1-dibromo-2,2-diphenyl- (6CI,7CI,8CI); 1,1-Dibromo-2,2-diphenylcyclopropane;NSC 156158

Chemical Property of 1,1-Dibromo-2-2-diphenylcyclopropane

Chemical Property:

• Vapor Pressure: 1.47E-05mmHg at 25°C
• Boiling Point: 377.4°Cat760mmHg
• Flash Point: 212.8°C
• PSA: 0.00000
• Density: 1.699g/cm³
• LogP: 4.86250

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,1-Dibromo-2-2-diphenylcyclopropane

There total 8 articles about 1,1-Dibromo-2-2-diphenylcyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,1-Diphenylethylene (530-48-3) + Bromoform (75-25-2) → 1,1-dibromo-2,2-diphenylcyclopropane (17343-74-7)

Guidance literature:

With potassium tert-butylate; In hexane; at 0 - 20 ℃; for 9h; Schlenk technique; Inert atmosphere;

DOI:10.1021/ja5032002

Reference yield:

benzophenone (119-61-9) → 1,1-dibromo-2,2-diphenylcyclopropane (17343-74-7)

Guidance literature:

Multi-step reaction with 2 steps

1: n-butyllithium / tetrahydrofuran / 48 h / 0 - 20 °C

2: sodium hydroxide / water; dichloromethane / 24 h / 25 °C

With n-butyllithium; sodium hydroxide; In tetrahydrofuran; dichloromethane; water;

DOI:10.1021/acs.orglett.5b01542

Reference yield:

Bromoform (75-25-2) + 3,3-diphenylpropene (3542-14-1) → 1,1-dibromo-2,2-diphenylcyclopropane (17343-74-7)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide; In water; at 50 - 60 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.8b01765

upstream raw materials:

1,1-Diphenylethylene

Bromoform

bromodiiodomethane

dibromoiodomethane

Downstream raw materials:

4-(2-bromo-3,3-diphenyl-allyl)-morpholine

1,1-diphenyl-1,2-propadiene

2,5-dibromo-1,1,6,6-tetraphenyl-hexa-1,5-diene

1,1-diphenylcyclopropane