Foramsulfuron

Base Information

• Chemical Name: Foramsulfuron
• CAS No.: 173159-57-4
• Molecular Formula: C17H20N6O7S
• Molecular Weight: 452.448
• Hs Code.: 29242990
• European Community (EC) Number: 605-666-1
• UNII: 4XJD212JQB
• ChEMBL ID: CHEMBL1243071
• DSSTox Substance ID: DTXSID7034753
• Nikkaji Number: J2.040.009I
• Wikidata: Q22807801
• Mol file: 173159-57-4.mol

Synonyms:Foramsulfuron;173159-57-4;2-(N-((4,6-Dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-4-formamido-N,N-dimethylbenzamide;4XJD212JQB;2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-4-formamido-N,N-dimethylbenzamide;CHEMBL1243071;CHEBI:83502;Benzamide, 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-4-(formylamino)-N,N-dimethyl-;2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)-4-formamido-N,N-dimethylbenzamide;Formasulfuron;Option 35WDG;Option Corn Herbicide;C17H20N6O7S;Foramsulfuron [ISO:BSI];UNII-4XJD212JQB;HSDB 7894;Benzamide, 2-(((((4,6-dimethoxy-2-pyrimidinyl)amino)carbonyl)amino)sulfonyl)-4-(formylamino)-N,N-dimethyl-;FORAMSULFURON [MI];FORAMSULFURON [ISO];SCHEMBL116874;DTXSID7034753;PXDNXJSDGQBLKS-UHFFFAOYSA-N;BDBM50326179;HY-W422402;1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)-5-formamidophenylsulfonyl]urea;NCGC00168314-01;AM20120621;CS-0569282;NS00000389;Foramsulfuron, PESTANAL(R), analytical standard;J-010880;Q22807801;2-(N-(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl)-4-formamido-N,N-dimethylbenzamide;2-{[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-4-(formylamino)-N,N-dimethylbenzamide;N,N-DIMETHYL-2-3-(4,6-DIMETHOXYPYRIMIDIN-2-YL)UREIDOSULFONYL-4-FORMYLAMINOBENZAMIDE;2-(((((4,6-DIMETHOXY-2-PYRIMIDINYL)AMINO)CARBONYL)AMINO)SULFONYL)-4-(FORMYLAMINO)-N,N-DIMETHYLBENZAMIDE;2-{[(4,6-DIMETHOXYPYRIMIDIN-2-YL)CARBAMOYL]AMINOSULFONYL}-4-FORMAMIDO-N,N-DIMETHYLBENZAMIDE;N,N-Dimethyl 2-(N-(N-(4,6-dimethoxypyrimid-2-yl)-aminocarbonyl)-aminosulfonyl)4-formamidobenzamide;N-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-5-formylamino-2-dimethylaminocarbonylbenzenesulfonamide

Chemical Property of Foramsulfuron

Chemical Property:

• Appearance/Colour: yellow-brownish
• Vapor Pressure: 4.2×10-11pa(20℃)
• Melting Point: 0-6oC
• Refractive Index: 1.613
• PKA: Dissociation constant (pKa at 21.5 °C) 4.6
• PSA: 177.30000
• Density: 1.471 g/cm³
• LogP: 2.52790
• Storage Temp.: 0-6°C
• Solubility.: Solubility in organic solvents (g/l at 20 °C) Acetone 1.925 Acetonitrile 1.111 1,2-Dichloroethane 0.185 Ethyl acetate 0.362 n-Heptane <0.010 Methanol 1.660 p-Xylene <0.010
• Water Solubility.: Solubility in water (g/l at 20 °C) 0.037 (pH 5) 3.293 (pH 7) 94.577 (pH 8)
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 7
• Exact Mass: 452.11141817
• Heavy Atom Count: 31
• Complexity: 732

Purity/Quality:

98%,99%, ^*data from raw suppliers

Foramsulfuron ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC
• Uses: Herbicide. Foramsulfuron is used in weed control practises in reduced tillage production. It also functions as a new herbicide with ALS-inhibiting active ingredient for the control of troublesome weeds in sugar beet.

Technology Process of Foramsulfuron

There total 2 articles about Foramsulfuron which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4,6-dimethoxy-2-aminopyrimidine (36315-01-2,256642-28-1) + sodium isocyanate (917-61-3) + 2-(dimethylcarbamoyl)-5-carboxamidobenzenesulfonyl chloride + C18H28N4O5S*Na(1+)*Cl(1-) → foramsulfuron (173159-57-4)

Guidance literature:

sodium isocyanate; 2-(dimethylcarbamoyl)-5-carboxamidobenzenesulfonyl chloride; With triethylamine; In acetone; at 20 - 25 ℃; for 2h;

4,6-dimethoxy-2-aminopyrimidine; C₁₈H₂₈N₄O₅S*Na⁽¹⁺⁾*Cl^(1-); In acetone; at 20 - 45 ℃; for 2h; Reagent/catalyst; Solvent;

Reference yield:

N,N-dimethyl-4-amino-2-[[[[(4,6-dimethoxypyrimidin-2-yl)amino]carbonyl]amino]sulfonyl]benzamide (190520-75-3) → foramsulfuron (173159-57-4)

Guidance literature:

With formic acid; acetic anhydride; In dichloromethane;

upstream raw materials:

N,N-dimethyl-4-amino-2-[[[[(4,6-dimethoxypyrimidin-2-yl)amino]carbonyl]amino]sulfonyl]benzamide

4,6-dimethoxy-2-aminopyrimidine

sodium isocyanate