Pimprinine

Base Information

Chemical Name:Pimprinine
CAS No.:13640-26-1
Molecular Formula:C12H10 N2 O
Molecular Weight:198.224
Hs Code.:29349990
NSC Number:80793
UNII:CRW4NIT4W1
DSSTox Substance ID:DTXSID80159782
Nikkaji Number:J14.303K
Wikidata:Q77375798
Metabolomics Workbench ID:113182
Mol file:13640-26-1.mol

Synonyms:5,3'-indolyl-2-methyloxazole;pimprinine

Suppliers and Price of Pimprinine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
Pimprinine ≥95%
5mg
$ 178.00

Cayman Chemical
Pimprinine ≥95%
1mg
$ 89.00

American Custom Chemicals Corporation
PIMPRININE 95.00%
5MG
$ 543.00

American Custom Chemicals Corporation
PIMPRININE 95.00%
1MG
$ 487.20

AK Scientific
Pimprinine
5mg
$ 618.00

Adipogen Life Sciences
Pimprinine ≥98%(HPLC,NMR)
5 mg
$ 390.00

Total 8 raw suppliers

Chemical Property of Pimprinine

Chemical Property:

Vapor Pressure:1.74E-06mmHg at 25°C
Melting Point:213.5 °C (polymorph)
Boiling Point:407.8°Cat760mmHg
PKA:15.78±0.30(Predicted)
Flash Point:210°C
PSA：41.82000
Density:1.243g/cm³
LogP:3.13130
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:198.079312947
Heavy Atom Count:15
Complexity:234

Purity/Quality:

98%min ^*data from raw suppliers

Pimprinine ≥95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C(O1)C2=CNC3=CC=CC=C32
Uses Pimprinine is an indole alkaloid produced by many species of Streptomyces. Pimprinine is a potent inhibitor of monoamine oxidase. More recently, pimprinine showed promising anticonvulsant activity in electric seizure threshold tests in mice, comparable to phenylhydantoin. Pimprinine also inhibits tremorine-induced tremors and analgesia in mice.

Technology Process of Pimprinine

There total 30 articles about Pimprinine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 73053-91-5
34N

: 13640-26-1
pimprinine

Guidance literature:: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; In ethyl acetate; acetonitrile; at 100 ℃; for 1h; Microwave irradiation;
DOI:10.1016/j.tetlet.2019.04.024

Reference yield: 100.0%

: 5-(1-benzenesulfonylindol-3-yl)-2-methyloxazole

: 13640-26-1
pimprinine

Guidance literature:: With water; sodium hydroxide; In methanol; at 55 ℃; for 4h;
DOI:10.1021/ol1019597

Reference yield: 99.0%

: 98258-84-5
5-(1-methoxyindol-3-yl)-2-methyloxazole

: 13640-26-1
pimprinine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 1.5h; under 760.051 Torr;
DOI:10.3987/COM-19-14031