Methylergonovine

Base Information

Chemical Name:Methylergonovine
CAS No.:113-42-8
Deprecated CAS:479-03-8,78207-86-0,29477-86-9,29589-73-9
Molecular Formula:C20H25 N3 O2
Molecular Weight:339.437
Hs Code.:
European Community (EC) Number:204-027-0
UNII:W53L6FE61V
DSSTox Substance ID:DTXSID00904978
Nikkaji Number:J5.132B
Wikipedia:Methylergometrine
Wikidata:Q424477
NCI Thesaurus Code:C74105
RXCUI:6883
Pharos Ligand ID:L2WSJKLTBK56
Metabolomics Workbench ID:42727
ChEMBL ID:CHEMBL1201356
Mol file:113-42-8.mol

Synonyms:Méthergin;Methergin;Methergine;Methylergobasin;Methylergometrin;Methylergometrine;Methylergometrine Maleate;Methylergonovine;Methylergonovine Maleate

Suppliers and Price of Methylergonovine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYLERGONOVINE 95.00%
250MG
$ 976.27

American Custom Chemicals Corporation
METHYLERGONOVINE 95.00%
50MG
$ 648.83

Total 0 raw suppliers

Chemical Property of Methylergonovine

Chemical Property:

Vapor Pressure:3.6E-17mmHg at 25°C
Melting Point:172-173℃ (decomposition)
Refractive Index:1.6650 (estimate)
Boiling Point:638.4 °C at 760 mmHg
PKA:pKa 6.65± 0.03(H2O,t =24,I<0.01)(Approximate)
Flash Point:339.9 °C
PSA：68.36000
Density:1.28 g/cm³
LogP:2.25350
Storage Temp.:Desiccate at RT
XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:339.19467705
Heavy Atom Count:25
Complexity:549

Purity/Quality:: METHYLERGONOVINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(CO)NC(=O)C1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
Isomeric SMILES:CC[C@@H](CO)NC(=O)[C@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C
Recent ClinicalTrials:Prophylactic Methylergonovine for Twin Cesarean
Recent EU Clinical Trials:Efficacy of methylergometrine daily administration in puerperium
Uses Methylergonovine is a drug currently used as a smooth muscle constrictor during postpartum hemorrhage, as an inhibitor of the inflammasome complex in ASC-mediated procaspase-1 activation screening. METHYLERGONOVINE is a homologue of ergonovine.It is used in the treatment of postpartumhemorrhage. Oxytocic.
Therapeutic Function Oxytocic

Technology Process of Methylergonovine

There total 9 articles about Methylergonovine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%