Melosatin A

Base Information

Chemical Name:Melosatin A
CAS No.:64838-04-6
Molecular Formula:C₂₁H₂₃NO₄
Molecular Weight:353.418
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40215131
Nikkaji Number:J19.533B
Wikidata:Q27107319
Metabolomics Workbench ID:68365
Mol file:64838-04-6.mol

Synonyms:Melosatin A;64838-04-6;C09221;AC1L4JIU;AC1Q6J8L;6,7-dimethoxy-4-(5-phenylpentyl)-1h-indole-2,3-dione;6,7-dimethoxy-4-(5-phenylpentyl)indoline-2,3-dione;CHEBI:6739;DTXSID40215131;Q27107319;1H-Indole-2,3-dione, 6,7-dimethoxy-4-(5-phenylpentyl)-

Suppliers and Price of Melosatin A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Melosatin A

Chemical Property:

PSA：64.63000
Density:1.183g/cm³
LogP:3.93210
XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:353.16270821
Heavy Atom Count:26
Complexity:488

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C2=C(C(=C1)CCCCCC3=CC=CC=C3)C(=O)C(=O)N2)OC

Technology Process of Melosatin A

There total 5 articles about Melosatin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22027-96-9
5-nitroveratral

: 64838-04-6
melosatin A

Guidance literature:: Multi-step reaction with 4 steps

1: 35 percent / aq. NaOH / ethanol / 3 h

2: 1.) NaBH₄, 2.) H₂ / 2.) Pd-C / 1.) MeOH, room temp., 4 h, 2.) 5 h

3: 1.) P₂O₅, 2.) H₂ / 2.) Pd-C / 1.) benzene, reflux, 24 h, 2.) MeOH, 4 h

4: 2 h / 165 - 170 °C

With sodium hydroxide; sodium tetrahydroborate; hydrogen; phosphorus pentoxide; palladium on activated charcoal; In ethanol;
DOI:10.1016/0040-4020(80)80221-3

Reference yield:

: 6635-20-7
isonitrovanillin

: 64838-04-6
melosatin A

Guidance literature:: Multi-step reaction with 5 steps

1: methanol; diethyl ether / 96 h

2: 35 percent / aq. NaOH / ethanol / 3 h

3: 1.) NaBH₄, 2.) H₂ / 2.) Pd-C / 1.) MeOH, room temp., 4 h, 2.) 5 h

4: 1.) P₂O₅, 2.) H₂ / 2.) Pd-C / 1.) benzene, reflux, 24 h, 2.) MeOH, 4 h

5: 2 h / 165 - 170 °C

With sodium hydroxide; sodium tetrahydroborate; hydrogen; phosphorus pentoxide; palladium on activated charcoal; In methanol; diethyl ether; ethanol;
DOI:10.1016/0040-4020(80)80221-3

Reference yield:

: 64838-05-7
1-phenyl-5-(3,4-dimethoxy-5-nitrophenyl)-1,4-pentadiene-3-one

: 64838-04-6
melosatin A

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaBH₄, 2.) H₂ / 2.) Pd-C / 1.) MeOH, room temp., 4 h, 2.) 5 h

2: 1.) P₂O₅, 2.) H₂ / 2.) Pd-C / 1.) benzene, reflux, 24 h, 2.) MeOH, 4 h

3: 2 h / 165 - 170 °C

With sodium tetrahydroborate; hydrogen; phosphorus pentoxide; palladium on activated charcoal;
DOI:10.1016/0040-4020(80)80221-3