2''-amino-2''-deoxyarbekacin

Base Information

Chemical Name:2''-amino-2''-deoxyarbekacin
CAS No.:147920-22-7
Molecular Formula:C22H45 N7 O9
Molecular Weight:551.63
Hs Code.:
Mol file:147920-22-7.mol

Synonyms:2''-Amino-2''-deoxyarbekacin

Suppliers and Price of 2''-amino-2''-deoxyarbekacin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2''-AMINO-2''-DEOXYARBEKACIN 95.00%
5MG
$ 497.55

Total 2 raw suppliers

Chemical Property of 2''-amino-2''-deoxyarbekacin

Chemical Property:

Boiling Point:880.9°Cat760mmHg
PKA:13.11±0.20(Predicted)
Flash Point:486.5°C
PSA：306.55000
Density:1.44g/cm³
LogP:-1.39090

Purity/Quality:: 2''-AMINO-2''-DEOXYARBEKACIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2''-amino-2''-deoxyarbekacin

There total 9 articles about 2''-amino-2''-deoxyarbekacin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: C₅₈H₈₉N₇O₂₁

: 147920-22-7
2''-amino-2''-deoxyarbekacin

Guidance literature:: With water; trifluoroacetic acid; for 1h; Ambient temperature;
DOI:10.7164/antibiotics.47.821

Reference yield:

: 3,2',6'-tris(N-tert-butoxycarbonyl)dibekacin

: 147920-22-7
2''-amino-2''-deoxyarbekacin

Guidance literature:: Multi-step reaction with 8 steps

1: 80 percent / pyridine / dimethylformamide / 4 h / Ambient temperature

2: 72 percent / p-toluenesulfonic acid / dimethylformamide / 1 h / 40 °C / 20 Torr

3: 1.) pyridinium trifluoroacetate, DMSO, dicyclohexylcarbodiimide, 2.) oxalic acid dihydrate / 1.) C₆H₆, r.t., overnight, 2.) C₆H₆, dioxane, r.t., 30 min

4: NH₄OAc, NaBH₃CN / methanol / Ambient temperature

5: 23 percent / Et₃N / tetrahydrofuran; methanol / Ambient temperature

6: 87 percent / 88percent HCOOH / 10percent Pd/C / methanol / 2 h / Ambient temperature

7: 139 mg / Et₃N / tetrahydrofuran / 5 deg C - 20 deg C

8: 27 percent / 90percent CF₃COOH/H₂O / 1 h / Ambient temperature

With pyridine; formic acid; ammonium acetate; water; pyridinium trifluroacetate; oxalic acid; sodium cyanoborohydride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.7164/antibiotics.47.821

Reference yield:

: 161909-27-9
1,3''-bis(N-benzyloxycarbonyl)-3,2',6'-tris(N-tert-butoxycarbonyl)dibekacin

: 147920-22-7
2''-amino-2''-deoxyarbekacin

Guidance literature:: Multi-step reaction with 7 steps

1: 72 percent / p-toluenesulfonic acid / dimethylformamide / 1 h / 40 °C / 20 Torr

2: 1.) pyridinium trifluoroacetate, DMSO, dicyclohexylcarbodiimide, 2.) oxalic acid dihydrate / 1.) C₆H₆, r.t., overnight, 2.) C₆H₆, dioxane, r.t., 30 min

3: NH₄OAc, NaBH₃CN / methanol / Ambient temperature

4: 23 percent / Et₃N / tetrahydrofuran; methanol / Ambient temperature

5: 87 percent / 88percent HCOOH / 10percent Pd/C / methanol / 2 h / Ambient temperature

6: 139 mg / Et₃N / tetrahydrofuran / 5 deg C - 20 deg C

7: 27 percent / 90percent CF₃COOH/H₂O / 1 h / Ambient temperature

With formic acid; ammonium acetate; water; pyridinium trifluroacetate; oxalic acid; sodium cyanoborohydride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.7164/antibiotics.47.821