1-(But-2-yn-1-yloxy)-4-methoxybenzene

Base Information

Chemical Name:1-(But-2-yn-1-yloxy)-4-methoxybenzene
CAS No.:41580-74-9
Molecular Formula:C11H12O2
Molecular Weight:176.215
Hs Code.:
NSC Number:86586
DSSTox Substance ID:DTXSID40292962
Wikidata:Q82031488

Synonyms:41580-74-9;NSC 86586;1-(but-2-yn-1-yloxy)-4-methoxybenzene;NSC86586;NCIOpen2_001185;DTXSID40292962;NSC-86586

Suppliers and Price of 1-(But-2-yn-1-yloxy)-4-methoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(But-2-yn-1-yloxy)-4-methoxybenzene

Chemical Property:

Vapor Pressure:0.00364mmHg at 25°C
Boiling Point:290.3°C at 760 mmHg
Flash Point:118.5°C
Density:1.034g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:176.083729621
Heavy Atom Count:13
Complexity:191

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC#CCOC1=CC=C(C=C1)OC

Technology Process of 1-(But-2-yn-1-yloxy)-4-methoxybenzene

There total 5 articles about 1-(But-2-yn-1-yloxy)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 150-76-5
4-methoxy-phenol

: 3355-28-0
1-Bromo-2-butyne

: 41580-74-9
1-(but-2-yn-1-yloxy)-4-methoxybenzene

Guidance literature:: With potassium carbonate; In acetone; at 60 ℃; for 6h;
DOI:10.1021/ol0489898

Reference yield: 75.0%

: 17061-86-8
1-methoxy-4-(2-propynyloxy)benzene

: 74-88-4
methyl iodide

: 41580-74-9
1-(but-2-yn-1-yloxy)-4-methoxybenzene

Guidance literature:: 1-methoxy-4-(2-propynyloxy)benzene; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 0.333333h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; hexane; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1039/c4ob02033b

Reference yield:

: 150-76-5
4-methoxy-phenol

: 41580-74-9
1-(but-2-yn-1-yloxy)-4-methoxybenzene

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / acetone

2: Na, liq. NH₃ / diethyl ether

With ammonia; sodium; potassium carbonate; In diethyl ether; acetone;
DOI:10.1021/ja01469a045