2-Amino-4-[(3,4-diaminophenyl)sulfonyl]phenylamine

Base Information

• Chemical Name: 2-Amino-4-[(3,4-diaminophenyl)sulfonyl]phenylamine
• CAS No.: 13224-79-8
• Molecular Formula: C12H14 N4 O2 S
• Molecular Weight: 278.335
• Hs Code.: 2921590090
• NSC Number: 86043
• DSSTox Substance ID: DTXSID00292842
• Nikkaji Number: J578.827G
• Wikidata: Q82031316
• Mol file: 13224-79-8.mol

Synonyms:13224-79-8;2-amino-4-[(3,4-diaminophenyl)sulfonyl]phenylamine;4-(3,4-diaminophenyl)sulfonylbenzene-1,2-diamine;4,4'-Sulfonylbis(benzene-1,2-diamine);1,2-Benzenediamine, 4,4'-sulfonylbis-;4,4'-sulfonyldibenzene-1,2-diamine;3,3',4,4'-tetraaminodiphenyl sulfone;3,3',4,4'-Tetraaminodiphenylsulfone;NSC86043;Cambridge id 5180142;Oprea1_287497;SCHEMBL636445;YSCK0149;DTXSID00292842;NSC-86043;STK503741;3,3',4,4'-tetraminodiphenyl sulfone;AKOS000601248;4,4'-Sulfonyldi(benzene-1,2-diamine);BS-52960;BB 0260828;CS-0111306;FT-0679192;E76027;SR-01000391088;J-006149;SR-01000391088-1

Chemical Property of 2-Amino-4-[(3,4-diaminophenyl)sulfonyl]phenylamine

Chemical Property:

• Vapor Pressure: 7.75E-16mmHg at 25°C
• Melting Point: 174 °C
• Boiling Point: 631.1°Cat760mmHg
• PKA: 2.36±0.10(Predicted)
• Flash Point: 335.5°C
• PSA: 146.60000
• Density: 1.489g/cm³
• LogP: 4.25380
• XLogP3: 0
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 278.08374688
• Heavy Atom Count: 19
• Complexity: 376

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-4-[(3,4-diaminophenyl)sulfonyl]phenylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1S(=O)(=O)C2=CC(=C(C=C2)N)N)N)N

Technology Process of 2-Amino-4-[(3,4-diaminophenyl)sulfonyl]phenylamine

There total 11 articles about 2-Amino-4-[(3,4-diaminophenyl)sulfonyl]phenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N,N'-[4,4'-sulfinylbis(2-nitrobenzenamine)] (18491-91-3) → 3,3',4,4'-Tetraaminodiphenylsulfon (13224-79-8)

Guidance literature:

With palladium 10% on activated carbon; hydrazine hydrate; In ethanol; at 60 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c4cc05964f

Reference yield:

4,4'-dichlorodiphenyl sulphone (80-07-9,30605-10-8,85228-26-8,36313-66-3) → 3,3',4,4'-Tetraaminodiphenylsulfon (13224-79-8)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂SO₄; HNO₃

2: alcohol; ammonia / 150 °C

3: tin dichloride

With ethanol; sulfuric acid; ammonia; nitric acid; tin(ll) chloride;

Reference yield:

bis(4-chloro-3-nitrophenyl)sulfone (1759-05-3) → 3,3',4,4'-Tetraaminodiphenylsulfon (13224-79-8)

Guidance literature:

Multi-step reaction with 2 steps

1: alcohol; ammonia / 150 °C

2: tin dichloride

With ethanol; ammonia; tin(ll) chloride;

upstream raw materials:

acedapsone

N,N'-[4,4'-sulfinylbis(2-nitrobenzenamine)]

4,4'-dichlorodiphenyl sulphone

bis(4-chloro-3-nitrophenyl)sulfone

Downstream raw materials:

2,2'-diphenyl-5,5'-sulfonyldibenzimidazole

C₃₀H₂₄N₆O₆S

C₃₀H₂₀Cl₄N₆O₆S

C₂₈H₁₈I₂N₆O₄S