Phenol, p-(3,4-dihydro-2,2-dimethyl-7-methoxy-4-phenyl-2H-1-benzopyran-3-yl)-, trans-

Base Information

Chemical Name:Phenol, p-(3,4-dihydro-2,2-dimethyl-7-methoxy-4-phenyl-2H-1-benzopyran-3-yl)-, trans-
CAS No.:84394-35-4
Molecular Formula:C24H24O3
Molecular Weight:360.4456
Hs Code.:
UNII:2Y4E1P367O

Synonyms:2Y4E1P367O;UNII-2Y4E1P367O;Phenol, p-(3,4-dihydro-2,2-dimethyl-7-methoxy-4-phenyl-2H-1-benzopyran-3-yl)-, trans-;84394-35-4;BRN 6069039;p-(3,4-Dihydro-2,2-dimethyl-7-methoxy-4-phenyl-2H-1-benzopyran-3-yl)-phenol, trans-(+/-)-;p-(2,2-Dimethyl-7-methoxy-4-phenyl-3-chromanyl)phenol;trans-p-(3,4-Dihydro-2,2-dimethyl-7-methoxy-4-phenyl-2H-1-benzopyran-3-yl)phenol;DES(2-PYRROLIDIN-1-YLETHOXY)-3-DEPHENYL-3-P-HYDROXY PHENYL CENTCHROMAN;DES(2-PYRROLIDIN-1-YLETHOXY)-3-DEPHENYL-3-P-HYDROXY PHENYL ORMELOXIFENE

Suppliers and Price of Phenol, p-(3,4-dihydro-2,2-dimethyl-7-methoxy-4-phenyl-2H-1-benzopyran-3-yl)-, trans-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Phenol, p-(3,4-dihydro-2,2-dimethyl-7-methoxy-4-phenyl-2H-1-benzopyran-3-yl)-, trans-

Chemical Property:

Vapor Pressure:1.39E-09mmHg at 25°C
Boiling Point:473.3°C at 760 mmHg
Flash Point:240.1°C
Density:1.138g/cm³
XLogP3:5.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:360.17254462
Heavy Atom Count:27
Complexity:476

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(C(C2=C(O1)C=C(C=C2)OC)C3=CC=CC=C3)C4=CC=C(C=C4)O)C
Isomeric SMILES:CC1([C@H]([C@@H](C2=C(O1)C=C(C=C2)OC)C3=CC=CC=C3)C4=CC=C(C=C4)O)C

Technology Process of Phenol, p-(3,4-dihydro-2,2-dimethyl-7-methoxy-4-phenyl-2H-1-benzopyran-3-yl)-, trans-

There total 5 articles about Phenol, p-(3,4-dihydro-2,2-dimethyl-7-methoxy-4-phenyl-2H-1-benzopyran-3-yl)-, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 84394-24-1
4-((3S,4R)-7-Methoxy-2,2-dimethyl-4-phenyl-chroman-3-yl)-phenol

: 84394-35-4
4-((3S,4S)-7-Methoxy-2,2-dimethyl-4-phenyl-chroman-3-yl)-phenol

Guidance literature:: With n-butyllithium; In hexane; dimethyl sulfoxide; for 16h; Ambient temperature;
DOI:10.1021/jm00358a026

Reference yield:

: 156-38-7
4-hydroxyphenylacetate

: 84394-35-4
4-((3S,4S)-7-Methoxy-2,2-dimethyl-4-phenyl-chroman-3-yl)-phenol

Guidance literature:: Multi-step reaction with 4 steps

1: 71 percent / NEt₃ / 10 h / Heating

2: 56 percent / diethyl ether; tetrahydrofuran / 4 h / Heating

3: 76 percent / H₂ / 10percent Pd/C / methanol / 8 h / 3102.9 Torr

4: 84 percent / n-BuLi / hexane; dimethylsulfoxide / 16 h / Ambient temperature

With n-butyllithium; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; hexane; dimethyl sulfoxide;
DOI:10.1021/jm00358a026

Reference yield:

: 131-57-7,897050-18-9
Benzophenone-3

: 84394-35-4
4-((3S,4S)-7-Methoxy-2,2-dimethyl-4-phenyl-chroman-3-yl)-phenol

Guidance literature:: Multi-step reaction with 4 steps

1: 71 percent / NEt₃ / 10 h / Heating

2: 56 percent / diethyl ether; tetrahydrofuran / 4 h / Heating

3: 76 percent / H₂ / 10percent Pd/C / methanol / 8 h / 3102.9 Torr

4: 84 percent / n-BuLi / hexane; dimethylsulfoxide / 16 h / Ambient temperature

With n-butyllithium; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; hexane; dimethyl sulfoxide;
DOI:10.1021/jm00358a026