3-Cytidylic acid, 5-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(2-chlorophenyl)-2-deoxy-N-(2-methyl-1-oxopropyl)guanylyl-(3.5)-N-benzoyl-2-deoxy-, 2-chlorophenyl 2-cyanoethyl ester

Base Information

Chemical Name:3-Cytidylic acid, 5-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(2-chlorophenyl)-2-deoxy-N-(2-methyl-1-oxopropyl)guanylyl-(3.5)-N-benzoyl-2-deoxy-, 2-chlorophenyl 2-cyanoethyl ester
CAS No.:78098-93-8
Molecular Formula:C₆₆H₆₃Cl₂N₉O₁₇P₂
Molecular Weight:1387.13
Hs Code.:

3-Cytidylic acid, 5-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(2-chlorophenyl)-2-deoxy-N-(2-methyl-1-oxopropyl)guanylyl-(3.5)-N-benzoyl-2-deoxy-, 2-chlorophenyl 2-cyanoethyl ester

Synonyms:

Suppliers and Price of 3-Cytidylic acid, 5-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(2-chlorophenyl)-2-deoxy-N-(2-methyl-1-oxopropyl)guanylyl-(3.5)-N-benzoyl-2-deoxy-, 2-chlorophenyl 2-cyanoethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Cytidylic acid, 5-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(2-chlorophenyl)-2-deoxy-N-(2-methyl-1-oxopropyl)guanylyl-(3.5)-N-benzoyl-2-deoxy-, 2-chlorophenyl 2-cyanoethyl ester

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-Cytidylic acid, 5-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(2-chlorophenyl)-2-deoxy-N-(2-methyl-1-oxopropyl)guanylyl-(3.5)-N-benzoyl-2-deoxy-, 2-chlorophenyl 2-cyanoethyl ester

There total 17 articles about 3-Cytidylic acid, 5-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(2-chlorophenyl)-2-deoxy-N-(2-methyl-1-oxopropyl)guanylyl-(3.5)-N-benzoyl-2-deoxy-, 2-chlorophenyl 2-cyanoethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 80817-38-5
N⁴-benzoyl-2'-deoxycytidine-3'-O-(2-chlorophenyl-2-cyanoethyl)phosphate

: 81187-01-1
Phosphoric acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester

: 78098-93-8
C₆₆H₆₃Cl₂N₉O₁₇P₂

Guidance literature:: With 1-(2,4,6-triisopropylbenzenesulfonyl)-3-nitro-1,2,4-triazole; In pyridine; at 20 ℃; for 3.5h;
DOI:10.1002/hlca.19820650803

Reference yield:

: 72351-28-1
2-chlorophenyl phosphordi(1H-1-[1,2,4]triazolide)

: 78098-93-8
C₆₆H₆₃Cl₂N₉O₁₇P₂

Guidance literature:: Multi-step reaction with 4 steps

1: dioxane / 2 h / 20 °C

2: 1-methylimidazole / dioxane / 3 h / 20 °C

3: triethylamine / pyridine / 3 h / 20 °C

4: 71 percent / 1-(2,4,6-triisopropylbenzenesulfonyl)-3-nitro-1,2,4-triazole / pyridine / 3.5 h / 20 °C

With 1-(2,4,6-triisopropylbenzenesulfonyl)-3-nitro-1,2,4-triazole; triethylamine; 1-methyl-1H-imidazole; In 1,4-dioxane; pyridine;
DOI:10.1002/hlca.19820650803

Reference yield:

: 68892-41-1
5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine

: 78098-93-8
C₆₆H₆₃Cl₂N₉O₁₇P₂

Guidance literature:: Multi-step reaction with 4 steps

1: dioxane / 2 h / 20 °C

2: 1-methylimidazole / dioxane / 3 h / 20 °C

3: triethylamine / pyridine / 3 h / 20 °C

4: 71 percent / 1-(2,4,6-triisopropylbenzenesulfonyl)-3-nitro-1,2,4-triazole / pyridine / 3.5 h / 20 °C

With 1-(2,4,6-triisopropylbenzenesulfonyl)-3-nitro-1,2,4-triazole; triethylamine; 1-methyl-1H-imidazole; In 1,4-dioxane; pyridine;
DOI:10.1002/hlca.19820650803