2-Chloro-6-fluorobenzoyl chloride

Base Information

• Chemical Name: 2-Chloro-6-fluorobenzoyl chloride
• CAS No.: 79455-63-3
• Molecular Formula: C7H3Cl2FO
• Molecular Weight: 193.005
• Hs Code.: 29163990
• European Community (EC) Number: 279-162-1
• DSSTox Substance ID: DTXSID20229695
• Nikkaji Number: J319.272E
• Wikidata: Q72450515
• Mol file: 79455-63-3.mol

Synonyms:2-Chloro-6-fluorobenzoyl chloride;79455-63-3;2-chloro-6-fluorobenzene-1-carbonyl chloride;2-chloro-6-fluorobenzoylchloride;C7H3Cl2FO;EINECS 279-162-1;MFCD00178746;2-Chloro-6-fluoro-benzoyl chloride;Benzoyl chloride, 2-chloro-6-fluoro-;6-chloro-2-fluorobenzoyl chloride;SCHEMBL476873;C7-H3-Cl2-F-O;DTXSID20229695;2-fluoro-6-chlorobenzoyl chloride;GFNAJZAKJGKJCS-UHFFFAOYSA-N;2-chloro-6-fluoro benzoyl chloride;CK1089;AKOS009159342;2-chloro-6-fluoro-benzoic acid chloride;PS-10774;SY049328;C2229;FT-0611855;2-chloro-6-fluorobenzoyl chloride, AldrichCPR;EN300-215204;A839692;W-104262;F2190-0071

Chemical Property of 2-Chloro-6-fluorobenzoyl chloride

Chemical Property:

• Vapor Pressure: 0.16mmHg at 25°C
• Melting Point: 57oC
• Refractive Index: 1.525
• Boiling Point: 213.9 °C at 760 mmHg
• Flash Point: 83.2 °C
• PSA: 17.07000
• Density: 1.462 g/cm³
• LogP: 2.85810
• Sensitive.: Moisture Sensitive
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 191.9544983
• Heavy Atom Count: 11
• Complexity: 163

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-6-fluorobenzoyl Chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)Cl)C(=O)Cl)F

Technology Process of 2-Chloro-6-fluorobenzoyl chloride

There total 1 articles about 2-Chloro-6-fluorobenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-6-fluorobenzoic acid (434-75-3) → 2-chloro-6-fluorobenzoyl chloride (79455-63-3)

Guidance literature:

With thionyl chloride; for 12h; Heating;

DOI:10.1002/ps.2780410210

Reference yield: 100.0%

[3-fluoro-4-(methoxymethyl)phenyl]methanamine + 2-chloro-6-fluorobenzoyl chloride (79455-63-3) → 2-chloro-6-fluoro-N-{[3-fluoro-4-(methoxymethyl)phenyl]methyl}benzamide

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 3h; Cooling with ice;

Reference yield: 92.0%

methyl Pyrrole-2-carboxylate (1193-62-0) + 2-chloro-6-fluorobenzoyl chloride (79455-63-3) → methyl 4-(2-chloro-6-fluorobenzoyl)-1H-pyrrole-2-carboxylate

Guidance literature:

2-chloro-6-fluorobenzoyl chloride; With aluminum (III) chloride; In dichloromethane; at 0 ℃; for 0.166667h;

methyl Pyrrole-2-carboxylate; In dichloromethane; at 20 ℃; for 18h;

upstream raw materials:

2-chloro-6-fluorobenzoic acid

Downstream raw materials:

N-(Bis-methylsulfanyl-methylene)-2-chloro-6-fluoro-benzamide

2-(2-Chloro-6-fluoro-benzoyl)-malonic acid diethyl ester

1,1-dimethylethyl [(2-chloro-6-fluorophenyl)carbonyl]carbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 79455-63-3 2-Chloro-6-fluorobenzene-1-carbonyl chloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send