4-(Dimethylamino)benzaldehyde N-phenylthiosemicarbazone

Base Information

Chemical Name:4-(Dimethylamino)benzaldehyde N-phenylthiosemicarbazone
CAS No.:22043-39-6
Molecular Formula:C16H18N4S
Molecular Weight:298.4059
Hs Code.:2930909090
NSC Number:213888
UNII:UVB4PQC2TQ
ChEMBL ID:CHEMBL254119
Mol file:22043-39-6.mol

Synonyms:4-(Dimethylamino)benzaldehyde N-phenylthiosemicarbazone;22043-39-6;UVB4PQC2TQ;NSC213888;NSC 213888;NSC-213888;1-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-3-phenylthiourea;p-((Dimethylamino)benzylidene)-4-phenyl-thiosemicarbazide;2-((4-(Dimethylamino)phenyl)methylene)-N-phenylhydrazinecarbothioamide;(2E)-2-((4-(Dimethylamino)phenyl)methylene)-N-phenylhydrazinecarbothioamide;Hydrazinecarbothioamide, 2-((4-(dimethylamino)phenyl)methylene)-N-phenyl-;Hydrazinecarbothioamide, 2-((4-(dimethylamino)phenyl)methylene)-N-phenyl-, (2E)-;1332462-93-7;UNII-UVB4PQC2TQ;CHEMBL254119;SCHEMBL13381429;HBLLYJOWYYMLSE-SFQUDFHCSA-N;MFCD06465805;STK730505;AKOS001703915;AKOS002352734;AN-689/40156649;1-[(E)-(4-dimethylaminophenyl)methyleneamino]-3-phenyl-thiourea;(2E)-2-[4-(dimethylamino)benzylidene]-N-phenylhydrazinecarbothioamide;3-[(E)-{[4-(DIMETHYLAMINO)PHENYL]METHYLIDENE}AMINO]-1-PHENYLTHIOUREA

Suppliers and Price of 4-(Dimethylamino)benzaldehyde N-phenylthiosemicarbazone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-(Dimethylamino)benzaldehyde N-phenylthiosemicarbazone

Chemical Property:

Vapor Pressure:3.78E-08mmHg at 25°C
Boiling Point:446°C at 760 mmHg
Flash Point:223.5°C
PSA：71.75000
Density:1.12g/cm³
LogP:3.53700
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:298.12521776
Heavy Atom Count:21
Complexity:342

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=CC=C(C=C1)C=NNC(=S)NC2=CC=CC=C2
Isomeric SMILES:CN(C)C1=CC=C(C=C1)/C=N/NC(=S)NC2=CC=CC=C2

Technology Process of 4-(Dimethylamino)benzaldehyde N-phenylthiosemicarbazone

There total 4 articles about 4-(Dimethylamino)benzaldehyde N-phenylthiosemicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 103-72-0
phenyl isothiocyanate

: 100-10-7
4-dimethylamino-benzaldehyde

: 302-01-2,78206-91-4,119775-10-9,75013-58-0
hydrazine

: 22043-39-6
1-[4-(dimethylamino)benzylidene]-4-phenylthiosemicarbazide

Guidance literature:: In methanol; for 24h; Reflux;
DOI:10.1016/j.tetlet.2009.02.134

Reference yield:

: 100-10-7
4-dimethylamino-benzaldehyde

: 5351-69-9
4-Phenyl-3-thiosemicarbazide

: 22043-39-6
1-[4-(dimethylamino)benzylidene]-4-phenylthiosemicarbazide

Guidance literature:: With hydrogenchloride; In ethanol; Heating;
DOI:10.1007/BF00809296

Reference yield:

: 103-72-0
phenyl isothiocyanate

: 22043-39-6
1-[4-(dimethylamino)benzylidene]-4-phenylthiosemicarbazide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 20 °C

2: acetic acid / 4 h / 79 °C

With hydrazine hydrate; acetic acid; In ethanol;
DOI:10.1080/17415993.2016.1163698