4H-1-Benzopyran-4-one, 3-(2-fluorophenyl)-7-hydroxy-

Base Information

Chemical Name:4H-1-Benzopyran-4-one, 3-(2-fluorophenyl)-7-hydroxy-
CAS No.:127526-39-0
Molecular Formula:C15H9FO3
Molecular Weight:256.2286
Hs Code.:
DSSTox Substance ID:DTXSID90155598
Nikkaji Number:J270.629F
Wikidata:Q83023532
Mol file:127526-39-0.mol

Synonyms:3-(2-fluorophenyl)-7-hydroxy-4H-chromen-4-one;127526-39-0;4H-1-Benzopyran-4-one, 3-(2-fluorophenyl)-7-hydroxy-;BRN 4750872;3-(2-fluorophenyl)-7-hydroxychromen-4-one;3-(2-Fluorophenyl)-7-hydroxy-4H-1-benzopyran-4-one;starbld0013497;Oprea1_362197;DTXSID90155598;BBL034797;STL419941;AKOS016402952;LS-39668;VS-12677;CS-0334594;7-Hydroxy-3-(2-fluorophenyl)-4H-1-benzopyran-4-one

Suppliers and Price of 4H-1-Benzopyran-4-one, 3-(2-fluorophenyl)-7-hydroxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4H-1-Benzopyran-4-one, 3-(2-fluorophenyl)-7-hydroxy-

Chemical Property:

Vapor Pressure:9.64E-09mmHg at 25°C
Boiling Point:450.8°C at 760 mmHg
Flash Point:226.4°C
Density:1.408g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:256.05357231
Heavy Atom Count:19
Complexity:393

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=COC3=C(C2=O)C=CC(=C3)O)F

Technology Process of 4H-1-Benzopyran-4-one, 3-(2-fluorophenyl)-7-hydroxy-

There total 3 articles about 4H-1-Benzopyran-4-one, 3-(2-fluorophenyl)-7-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 121060-02-4
2,4-dihydroxyphenyl-2′-fluorobenzylketone

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 127526-39-0
3-(2-Fluoro-phenyl)-7-hydroxy-chromen-4-one

Guidance literature:: With boron trifluoride diethyl etherate; phosphorus trichloride; at 50 - 60 ℃;
DOI:10.1007/BF00767029

Reference yield:

: Formic acid 3-(2-fluoro-phenyl)-4-oxo-4H-chromen-7-yl ester

: 127526-39-0
3-(2-Fluoro-phenyl)-7-hydroxy-chromen-4-one

Guidance literature:: With triethylamine; formyl acetic anhydride; at 80 - 100 ℃; for 0.25h; Yield given;
DOI:10.1007/BF00475243

Reference yield:

: 121060-02-4
2,4-dihydroxyphenyl-2′-fluorobenzylketone

: 127526-39-0
3-(2-Fluoro-phenyl)-7-hydroxy-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / 0.17 h / 0 °C

2: mixed anhydride of acetic and formic acid, Et₃N / 0.25 h / 80 - 100 °C

With triethylamine; formyl acetic anhydride;
DOI:10.1007/BF00475243