Methyl 2-((3-(2-fluorophenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy)propanoate

Base Information

Chemical Name:Methyl 2-((3-(2-fluorophenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy)propanoate
CAS No.:131814-57-8
Molecular Formula:C19H15 F O5
Molecular Weight:342.3178
Hs Code.:
DSSTox Substance ID:DTXSID90927358

Synonyms:BRN 4763202;131814-57-8;Methyl 2-((3-(2-fluorophenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy)propanoate;Propanoic acid, 2-((3-(2-fluorophenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy)-, methyl ester;Methyl 2-{[3-(2-fluorophenyl)-4-oxo-4H-1-benzopyran-7-yl]oxy}propanoate;C19H15FO5;DTXSID90927358;LS-121463

Suppliers and Price of Methyl 2-((3-(2-fluorophenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 2-((3-(2-fluorophenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy)propanoate

Chemical Property:

Vapor Pressure:1.95E-09mmHg at 25°C
Boiling Point:481.7°Cat760mmHg
Flash Point:236.3°C
Density:1.312g/cm³
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:342.09035174
Heavy Atom Count:25
Complexity:546

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)OC)OC1=CC2=C(C=C1)C(=O)C(=CO2)C3=CC=CC=C3F

Technology Process of Methyl 2-((3-(2-fluorophenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy)propanoate

There total 2 articles about Methyl 2-((3-(2-fluorophenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 5445-17-0
Methyl 2-bromopropionate

: 127526-39-0
3-(2-Fluoro-phenyl)-7-hydroxy-chromen-4-one

: 131814-57-8
2-[3-(2-Fluoro-phenyl)-4-oxo-4H-chromen-7-yloxy]-propionic acid methyl ester

Guidance literature:: With potassium carbonate; In acetone; at 50 - 56 ℃; for 2h;
DOI:10.1007/BF00767029

Reference yield:

: 121060-02-4
2,4-dihydroxyphenyl-2′-fluorobenzylketone

: 131814-57-8
2-[3-(2-Fluoro-phenyl)-4-oxo-4H-chromen-7-yloxy]-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / boron trifluoride etherate, phosphorus trichloride / 50 - 60 °C

2: 95 percent / potassium carbonate / acetone / 2 h / 50 - 56 °C

With boron trifluoride diethyl etherate; potassium carbonate; phosphorus trichloride; In acetone;
DOI:10.1007/BF00767029