5-(N-tert-Butyl)amiloride

Base Information

Chemical Name:5-(N-tert-Butyl)amiloride
CAS No.:1152-29-0
Molecular Formula:C₁₀H₁₆ClN₇O
Molecular Weight:285.736
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10150984
Nikkaji Number:J378.710I
ChEMBL ID:CHEMBL445704
Mol file:1152-29-0.mol

Synonyms:5-(N-tert-butyl)amiloride;5-N-t-butylamiloride

Suppliers and Price of 5-(N-tert-Butyl)amiloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5-(N-tert-Butyl)amiloride

Chemical Property:

Vapor Pressure:1.13E-12mmHg at 25°C
Boiling Point:562.3°Cat760mmHg
Flash Point:293.9°C
PSA：149.52000
Density:1.55g/cm³
LogP:1.92380
XLogP3:0.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:285.1104859
Heavy Atom Count:19
Complexity:363

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)NC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N

Technology Process of 5-(N-tert-Butyl)amiloride

There total 2 articles about 5-(N-tert-Butyl)amiloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76599-75-2
N-(3-Amino-5,6-dichloro-pyrazine-2-carbonyl)-guanidine

: 75-64-9
tert-butylamine

: 1152-29-0
5-tert-butylamino-amiloride

Guidance literature:: With triethylamine; In dimethyl sulfoxide; at 80 - 120 ℃;
DOI:10.1016/j.bmcl.2009.03.029

Reference yield:

: 1152-29-0
2-(tert.-Butylamino)-3-chlor-6-amino-5-(N-guanyl-carbamoyl)-pyrazin

Guidance literature:: Guanidin, abs. Me., 2-(tert.-Butylamino)-3-chlor-6-amino-5-methoxycarbonyl-pyrazin (Siedetemp.,1min; 20grad, 1h);
DOI:10.1021/jm00313a014