Guvacoline

Base Information

Chemical Name:Guvacoline
CAS No.:495-19-2
Molecular Formula:C7H11 N O2
Molecular Weight:141.17
Hs Code.:
UNII:YT3OF85P98
DSSTox Substance ID:DTXSID20197805
Nikkaji Number:J11.505C
Wikipedia:Guvacoline
Wikidata:Q27149807
Metabolomics Workbench ID:129945
ChEMBL ID:CHEMBL268808
Mol file:495-19-2.mol

Synonyms:norarecoline

Suppliers and Price of Guvacoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
GuvacolineHydrobromide
10 mg
$ 860.00

Crysdot
Methyl1,2,5,6-tetrahydropyridine-3-carboxylate 97%
1g
$ 412.00

Crysdot
Methyl1,2,5,6-tetrahydropyridine-3-carboxylate 97%
25g
$ 2079.00

Crysdot
Methyl1,2,5,6-tetrahydropyridine-3-carboxylate 97%
5g
$ 932.00

Alichem
Methyl1,2,5,6-tetrahydropyridine-3-carboxylate
25g
$ 2680.00

Alichem
Methyl1,2,5,6-tetrahydropyridine-3-carboxylate
10g
$ 1591.92

Alichem
Methyl1,2,5,6-tetrahydropyridine-3-carboxylate
5g
$ 1302.48

Total 13 raw suppliers

Chemical Property of Guvacoline

Chemical Property:

Vapor Pressure:0.207mmHg at 25°C
Melting Point:144°C
Boiling Point:209.1°Cat760mmHg
Flash Point:80.2°C
PSA：38.33000
Density:1.074g/cm³
LogP:1.36600
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:141.078978594
Heavy Atom Count:10
Complexity:163

Purity/Quality:

98%Min ^*data from raw suppliers

GuvacolineHydrobromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CCCNC1
Uses 3-Pyridinecarboxylic acid can be used as a useful tool in the identification of muscarinic receptors.

Technology Process of Guvacoline

There total 7 articles about Guvacoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 63-75-2
arecoline

: 495-19-2
norarecoline

Guidance literature:: arecoline; With carbonochloridic acid 1-chloro-ethyl ester; In toluene; for 3h; Heating;

In methanol; at 20 ℃;
DOI:10.1016/S0968-0896(00)00291-1

Reference yield: 93.0%

: 1-(9H-fluoren-9-yl)methyl 3-methyl 1,2,5,6-tetrahydropyridine-1,3-dicarboxylate

: 495-19-2
norarecoline

Guidance literature:: With diethylamine; In acetonitrile; at 20 ℃; for 2.5h;
DOI:10.1016/j.ejmech.2020.112623

Reference yield: 85.0%

: 92600-27-6
1-(1-chloroethyl) 3-methyl 5,6-dihydropyridine-1,3(2H)-dicarboxylate

: 495-19-2
norarecoline

Guidance literature:: 1-(1-chloroethyl) 3-methyl 5,6-dihydropyridine-1,3(2H)-dicarboxylate; In methanol; for 2h; Reflux;

With potassium carbonate; In water; for 0.5h;
DOI:10.1002/anie.201301341