Pyrazino[1,2-a]indole-1,4-dione, 2,3-dihydro-2-methyl-3-methylene-

Base Information

Chemical Name:Pyrazino[1,2-a]indole-1,4-dione, 2,3-dihydro-2-methyl-3-methylene-
CAS No.:19079-11-9
Molecular Formula:C13H10 N2 O2
Molecular Weight:226.235
Hs Code.:2933990090
NSC Number:175900
DSSTox Substance ID:DTXSID90306366
Nikkaji Number:J104.652G
Wikidata:Q82053429
Metabolomics Workbench ID:164848
Mol file:19079-11-9.mol

Synonyms:19079-11-9;NSC175900;Pyrazino[1,2-a]indole-1,4-dione, 2,3-dihydro-2-methyl-3-methylene-;2-methyl-3-methylidenepyrazino[1,2-a]indole-1,4-dione;DTXSID90306366;NSC-175900;Pyrazino[1,4-dione, 2,3-dihydro-2-methyl-3-methylene-;1,2,3,4-tetrahydro-2-methyl-3-methylene-1,4-dioxopyrazino[1,2-a]indole;2-Methyl-3-methylene-2,3-dihydropyrazino[1,2-a]indole-1,4-dione #

Suppliers and Price of Pyrazino[1,2-a]indole-1,4-dione, 2,3-dihydro-2-methyl-3-methylene-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Pyrazino[1,2-a]indole-1,4-dione, 2,3-dihydro-2-methyl-3-methylene-

Chemical Property:

Vapor Pressure:0.000119mmHg at 25°C
Boiling Point:335.6°C at 760 mmHg
Flash Point:156.8°C
PSA：43.48000
Density:1.32g/cm³
LogP:0.28060
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:226.074227566
Heavy Atom Count:17
Complexity:404

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=C)C(=O)N2C3=CC=CC=C3C=C2C1=O

Technology Process of Pyrazino[1,2-a]indole-1,4-dione, 2,3-dihydro-2-methyl-3-methylene-

There total 4 articles about Pyrazino[1,2-a]indole-1,4-dione, 2,3-dihydro-2-methyl-3-methylene- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-99-2
gliotoxin

: 19079-11-9
1,2,3,4-tetrahydro-2-methyl-3-methylene-1,4-dioxopyrazino[1,2-a]indole

Guidance literature:: With aluminum oxide; In benzene; for 12h; Ambient temperature;

Reference yield:

: 3770-50-1,117770-52-2
2-carbethoxyindole

: 19079-11-9
1,2,3,4-tetrahydro-2-methyl-3-methylene-1,4-dioxopyrazino[1,2-a]indole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Sn, HCl; 2.) CH₃NH₂ / 1.) H₂O; 2.) H₂O

2: 1.) diisopropylethylamine; 2.) 2,3-dichloro-5,6-dicyano-1,4-benzoquinone, p-toluenesulphonic acid, Tos-OH / 1.) r.t., CCl₄, CH₂Cl₂, 1 h; 2.) dioxane, reflux, 16 h

With hydrogenchloride; tin; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; methylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone;

Reference yield:

: 77920-71-9
N-methylindole-2-carboxamide

: 5704-66-5
pyruvoyl chloride

: 19079-11-9
1,2,3,4-tetrahydro-2-methyl-3-methylene-1,4-dioxopyrazino[1,2-a]indole

Guidance literature:: With toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; Yield given. Multistep reaction; 1.) r.t., CCl₄, CH₂Cl₂, 1 h; 2.) dioxane, reflux, 16 h;