Spiro[5.6]dodecane

Base Information

Chemical Name:Spiro[5.6]dodecane
CAS No.:181-15-7
Molecular Formula:C₁₂H₂₂
Molecular Weight:166.307
Hs Code.:2902199090
NSC Number:169769
DSSTox Substance ID:DTXSID30171055
Nikkaji Number:J117.134H
Wikidata:Q83041100
Mol file:181-15-7.mol

Synonyms:Spiro[5.6]dodecane;SPIRO(5.6)DODECANE;181-15-7;Spiro(5,6)dodecane;NSC169769;spiro[6.5]dodecane;C123CCCCC1.C2CCCCC3;DTXSID30171055;ZDNANLAHKKNCTC-UHFFFAOYSA-N;NSC 169769;NSC-169769

Suppliers and Price of Spiro[5.6]dodecane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of Spiro[5.6]dodecane

Chemical Property:

Vapor Pressure:0.0554mmHg at 25°C
Refractive Index:1.4850 (estimate)
Boiling Point:241.6°Cat760mmHg
Flash Point:85.8°C
PSA：0.00000
Density:0.87g/cm³
LogP:4.29110
XLogP3:5.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:0
Exact Mass:166.172150702
Heavy Atom Count:12
Complexity:121

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCCC2(CC1)CCCCC2

Technology Process of Spiro[5.6]dodecane

There total 17 articles about Spiro[5.6]dodecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 4728-90-9
spiro[5.6]dodecan-7-one

: 181-15-7
Spiro<5.6>dodecan

Guidance literature:: spiro[5.6]dodecan-7-one; With hydrazine hydrate; In diethylene glycol; for 1.5h; Reflux;

With potassium tert-butylate; at 190 - 200 ℃; for 3h; Reagent/catalyst;
DOI:10.1039/c7cc05101h

Reference yield: 39.0%

: 4728-93-2
spiro<5.6>dodecan-7-one

: 181-15-7
Spiro<5.6>dodecan

Guidance literature:: DOI:10.1021/jo00178a017

Reference yield:

: 42540-18-1
<5.3.2>propellanone

: 181-15-7
Spiro<5.6>dodecan

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent / TsOH*H₂O / 15 h / 50 °C

2: 72 mg / LiAlH₄ / diethyl ether / 1 h / Ambient temperature

3: 76 percent / lead tetraacetate / benzene / 1 h / Ambient temperature

4: hydroquinone, boron trifluoride etherate / 69 h / Ambient temperature

5: Raney nickel (W-4) / ethanol / 4 h / Heating

With lead(IV) acetate; lithium aluminium tetrahydride; boron trifluoride diethyl etherate; toluene-4-sulfonic acid; hydroquinone; Raney nickel (W-4); In diethyl ether; ethanol; benzene;
DOI:10.1021/jo00178a017