5-(p-Chlorobenzyl)-6-aminouracil

Base Information

Chemical Name:5-(p-Chlorobenzyl)-6-aminouracil
CAS No.:73908-08-4
Molecular Formula:C11H10 Cl N3 O2
Molecular Weight:251.67
Hs Code.:
DSSTox Substance ID:DTXSID30224479
Wikidata:Q83103073
Mol file:73908-08-4.mol

Synonyms:5-(4-chlorobenzyl)-6-aminouracil;5-(p-chlorobenzyl)-6-aminouracil;5-ClAU

Suppliers and Price of 5-(p-Chlorobenzyl)-6-aminouracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-(p-Chlorobenzyl)-6-aminouracil

Chemical Property:

Melting Point:356 °C (decomp)
PKA:3.65±0.10(Predicted)
PSA：92.26000
Density:1.408g/cm³
LogP:2.29540
XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:251.0461543
Heavy Atom Count:17
Complexity:373

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC2=C(NC(=O)NC2=O)N)Cl

Technology Process of 5-(p-Chlorobenzyl)-6-aminouracil

There total 2 articles about 5-(p-Chlorobenzyl)-6-aminouracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 52906-62-4
3-(4-chloro-phenyl)-2-cyano-propionic acid ethyl ester

: 57-13-6
urea

: 73908-08-4
5-(p-Chlorobenzyl)-6-aminouracil

Guidance literature:: With ethanol; sodium; In ethanol; for 7h; Heating;
DOI:10.1021/jo01303a042

Reference yield:

: 104-83-6
1-Chloro-4-(chloromethyl)benzene

: 73908-08-4
5-(p-Chlorobenzyl)-6-aminouracil

Guidance literature:: Multi-step reaction with 2 steps

1: 1) sodium ethoxide or sodium hydride

2: 54 percent / sodium, ethanol / ethanol / 7 h / Heating

With ethanol; sodium ethoxide or sodium hydride; sodium; In ethanol;
DOI:10.1021/jo01303a042